Dranka-Bojarowska Daria, Lewiński Adam
Śląski Uniwersytet Medyczny, Wydział Lekarski, Klinika Chirurgii Przewodu Pokarmowego, Katowice.
Pol Przegl Chir. 2019 Jan 8;91(5):51-57. doi: 10.5604/01.3001.0012.8371.
Treatment of squamous cell carcinoma is associated with an increased risk of other primary malignancies, mainly within the head and neck, as well as in the oesophageal gastric graft. More frequent recognition of multiple primary cancers associated with esophageal cancer, both synchronous and metachronous, is associated with longer follow-up after radical cancer treatment for esophageal cancer and high quality diagnostic procedures, both before and after surgery. The paper reviews the available literature and describes the molecular basis of the formation of multiple primary tumors associated with squamous cell carcinoma of the esophagus.
鳞状细胞癌的治疗与其他原发性恶性肿瘤风险增加相关,主要发生在头颈部以及食管胃移植物中。对与食管癌相关的多原发性癌症(包括同时性和异时性)的更频繁识别,与食管癌根治性癌症治疗后更长时间的随访以及手术前后高质量的诊断程序有关。本文综述了现有文献,并描述了与食管鳞状细胞癌相关的多原发性肿瘤形成的分子基础。