镍催化由甲硅烷基酮合成硅烷
Nickel-Catalyzed Synthesis of Silanes from Silyl Ketones.
作者信息
Srimontree Watchara, Lakornwong Waranya, Rueping Magnus
机构信息
Institute of Organic Chemistry , RWTH Aachen University , Landoltweg 1 , 52074 Aachen , Germany.
KAUST Catalysis Center (KCC) , King Abdullah University of Science and Technology (KAUST) , Thuwal 23955-6900 , Saudi Arabia.
出版信息
Org Lett. 2019 Dec 6;21(23):9330-9333. doi: 10.1021/acs.orglett.9b03487. Epub 2019 Nov 8.
An unprecedented nickel-catalyzed decarbonylative silylation via CO extrusion intramolecular recombination fragment coupling of unstrained and nondirecting group-assisted silyl ketones is described. The inexpensive and readily available catalyst performs under mild reaction conditions and enables the synthesis of structurally diverse arylsilanes, including heterocyclic and natural product derivatives.
本文描述了一种前所未有的镍催化脱羰硅基化反应，该反应通过CO挤出实现了无张力且无导向基团辅助的甲硅烷基酮的分子内重组片段偶联。这种廉价且易于获得的催化剂在温和的反应条件下即可发挥作用，能够合成结构多样的芳基硅烷，包括杂环和天然产物衍生物。
Zotero 插件