Larner Andrew J
Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool L9 7LJ, UK.
Diagnostics (Basel). 2019 Nov 7;9(4):180. doi: 10.3390/diagnostics9040180.
In this special issue of , expert contributors have produced up-to-date research studies and reviews on various topics related to the diagnosis of dementia and cognitive impairment. The methods of the assessments discussed extend from simple neurological signs, which may be elicited in the clinical encounter, through cognitive screening instruments, to sophisticated analyses of neuroimaging and cerebrospinal fluid biomarkers of disease. It is hoped that these various methods may facilitate earlier diagnosis of dementia and its subtypes, and provide differential diagnosis of depression and functional cognitive disorders, as a prelude to meaningful interventions.
在本期《》特刊中，专家撰稿人针对与痴呆症和认知障碍诊断相关的各类主题开展了最新的研究和综述。所讨论的评估方法范围广泛，从临床问诊中可能引出的简单神经学体征，到认知筛查工具，再到对疾病的神经影像学和脑脊液生物标志物的精细分析。希望这些多样的方法能够促进痴呆症及其亚型的早期诊断，并为抑郁症和功能性认知障碍提供鉴别诊断，作为有意义干预措施的前奏。
