Gynecology and Obstetrics 1, Department of Surgical Sciences, City of Health and Science, University of Torino, Torino, Italy.
Gynecology and Obstetrics 2, Department of Surgical Sciences, City of Health and Science, University of Torino, Torino, Italy.
BMC Infect Dis. 2019 Nov 8;19(1):952. doi: 10.1186/s12879-019-4595-x.
Osteomyelitis of the pubic symphysis is a rare cause of pelvic pain after delivery, mainly caused by Staphylococcus aureus and Pseudomonas aeruginosa. The clinical context is the same as the more common diastasis of the pubic bone, but the presence of intense local pain in association with fever should prompt further clinical work-up based on blood chemistry, microbiology and diagnostic imaging. We report the first case of methicillin-resistant Staphylococcus aureus osteomyelitis of the pubic symphysis occuring after the delivery.
A 39-year-old woman developed pain over the pubic bone 12 h after the delivery. After 72 h fever rose and laboratory examination showed elevation of C-reactive protein and procalcitonin levels. Pelvic x-rays and magnetic resonance showed pubic diastasis, joint effusion, tiny irregularities of articular surfaces and, severe bone edema. The patient was started on broad spectrum intravenous (IV) antibiotics (piperacillin-tazobactam) and then replaced to IV vancomycin and oral levofloxacin based on antibiogram result. She was then discharged with oral antibiotic therapy and fully recovered.
Due to the rarity of this disease, we compared our experience with the other cases of osteomyelitis of pubic symphysis occurring in peri-postpartum reported in the literature. The course of osteomyelitis was favourable in all patients, and only in one case an additional orthopedic procedure for symphysis fixation was necessary. Knowledge of this rare condition is important to enable prompt diagnosis and treatment.
耻骨联合骨髓炎是产后骨盆疼痛的罕见原因,主要由金黄色葡萄球菌和铜绿假单胞菌引起。临床情况与更常见的耻骨分离相同,但存在剧烈局部疼痛伴发热时,应根据血液化学、微生物学和诊断影像学进一步进行临床检查。我们报告首例产褥期后耐甲氧西林金黄色葡萄球菌耻骨联合骨髓炎病例。
一名 39 岁女性在分娩后 12 小时出现耻骨疼痛。72 小时后发热,实验室检查显示 C 反应蛋白和降钙素原水平升高。骨盆 X 线和磁共振成像显示耻骨分离、关节积液、关节表面微小不规则和严重骨水肿。患者开始接受广谱静脉(IV)抗生素(哌拉西林他唑巴坦)治疗,然后根据药敏结果更换为 IV 万古霉素和口服左氧氟沙星。随后患者出院接受口服抗生素治疗并完全康复。
由于这种疾病罕见,我们将我们的经验与文献中报道的其他围产期耻骨联合骨髓炎病例进行了比较。所有患者的骨髓炎病程均良好,仅 1 例需要额外的骨科耻骨固定术。了解这种罕见疾病很重要,以便能够及时诊断和治疗。