在埃塞俄比亚，接受门诊治疗的抑郁症患者的健康相关生活质量及其相关因素：一项横断面研究。
Health related quality of life and its correlates among people with depression attending outpatient department in Ethiopia: a cross sectional study.
机构信息
Department of Psychiatry, College of Health and Medical Science, Dilla University, Dilla, Ethiopia.
出版信息
Health Qual Life Outcomes. 2019 Nov 8;17(1):169. doi: 10.1186/s12955-019-1233-7.
BACKGROUND
Depression is a common mental disorder negatively affects the cognitive, emotion, behavior, functionality and quality of life of people. Poor quality of life results in high rates of relapse, inability to perform occupational and social activities, impaired future outlook, and increases overall health care related costs. However, there is no available evidence regarding the health related quality of people with depression in Ethiopia. Therefore, evaluating the quality of life of people with depression is crucial.
OBJECTIVE
The aim of this study was to assess the health related quality of life and its correlates among people with depression at Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia.
METHODS
An institutional based cross-sectional study was conducted from May to , 2018. A randomly selected 394 clients with depression were participated in this study. Health related quality of life was measured using world health organization quality of life brief. The collected data were coded and entered to SPSS version 20 for analysis. Step wise multiple linear regression analysis was used to identify the correlates of quality of life and the strength of the correlation was measured by β coefficient with 95% confidence interval.
RESULTS
The mean (±SD) scores of quality of life of people with depression were 41.3 ± 7.5, 42.8 ± 8.2, 38.9 ± 8.9 and 41.8 ± 6.5 for physical, psychological, social and environmental domains, respectively. The Multiple regression analysis showed that age of respondents, age of onset of depression, perceived stigma, living arrangement, social support level and duration of illness were statistically significant predictors of health related quality of life of people with depression in all or at least one domain of quality of life.
CONCLUSIONS
This study revealed that nearly half of study participants scored below the mean score in each domain of health related quality of life. This demonstrates a need for improving the quality of life of people with depression through the integration of a positive mental health approach and bio-psychosocial view together with the pharmacological treatments of depression. Moreover, strengthening social support, early identification and treatment of depression and prevention of stigma are also highly recommended to improve the quality of life of people with depression.
背景
抑郁症是一种常见的精神障碍，会对人的认知、情绪、行为、功能和生活质量产生负面影响。生活质量差会导致高复发率、无法进行职业和社会活动、未来前景受损以及整体医疗保健相关成本增加。然而，目前埃塞俄比亚还没有关于抑郁症患者健康相关生活质量的可用证据。因此，评估抑郁症患者的生活质量至关重要。
目的
本研究旨在评估埃塞俄比亚阿马努埃尔曼宁特殊精神医院抑郁症患者的健康相关生活质量及其相关因素。
方法
这是一项 2018 年 5 月至 月期间在阿马努埃尔曼宁特殊精神医院进行的基于机构的横断面研究。随机选择了 394 名抑郁症患者参与了这项研究。使用世界卫生组织生活质量简表来衡量健康相关生活质量。收集的数据进行编码并输入到 SPSS 版本 20 进行分析。采用逐步多元线性回归分析来确定生活质量的相关因素，并用β系数和 95%置信区间来衡量相关强度。
结果
抑郁症患者生活质量的平均（±SD）得分分别为：身体领域 41.3±7.5、心理领域 42.8±8.2、社会关系领域 38.9±8.9、环境领域 41.8±6.5。多元回归分析表明，受访者年龄、抑郁症发病年龄、感知耻辱感、居住安排、社会支持水平和病程长短是抑郁症患者健康相关生活质量的统计学显著预测因素，在所有或至少一个生活质量领域中都是如此。
结论
本研究表明，近一半的研究参与者在健康相关生活质量的每个领域的得分都低于平均分。这表明需要通过整合积极的心理健康方法和生物心理社会观点以及抗抑郁药物治疗来提高抑郁症患者的生活质量。此外，还强烈建议加强社会支持、早期识别和治疗抑郁症以及预防耻辱感，以提高抑郁症患者的生活质量。
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