Iacobellis Francesca, Di Serafino Marco, Blasio Roberta, Barbuto Luigi, Pezzullo Filomena, Romano Luigia
Department of General and Emergency Radiology, "A. Cardarelli" Hospital, Naples, Italy.
Department of Radiology, University of Naples "Federico II", Naples, Italy.
Am J Case Rep. 2019 Nov 10;20:1652-1658. doi: 10.12659/AJCR.916961.
BACKGROUND Secondary neurolymphomatosis is a rare clinical condition that may be observed in patients with hematologic malignancies. Clinical findings can overlap with other conditions. Diagnosis can be obtained by magnetic resonance imaging (MRI) and imaging with positron emission tomography (PET) and confirmed by biopsy. CASE REPORT A 55-year-old male patient with known previous history of periocular non-Hodgkin's lymphoma mucosa-associated lymphoid tissue (MALT) type presented reporting he had a focal soft-tissue swelling mass on the external side of the right arm, suspected for lipoma. US, MRI, and FDG PET/CT were performed, revealing malignant imaging characteristics of the lesion, suspected to be a neurolymphoma. A biopsy confirmed the nature of the lesion. No further sites of malignancy were detected on whole-body PET/CT. CONCLUSIONS Lymphomatous involvement of peripheral nerves may clinically overlap with other, more common, benign conditions; therefore, although it is rarer, this diagnosis has to be considered in patients with a clinical history of hematologic malignancies.
背景 继发性神经淋巴瘤病是一种罕见的临床病症，可在血液系统恶性肿瘤患者中观察到。临床表现可能与其他病症重叠。可通过磁共振成像（MRI）和正电子发射断层扫描（PET）成像进行诊断，并通过活检予以证实。病例报告 一名55岁男性患者，既往有眼周黏膜相关淋巴组织（MALT）型非霍奇金淋巴瘤病史，现报告其右臂外侧有一个局灶性软组织肿胀肿块，怀疑为脂肪瘤。进行了超声、MRI和氟代脱氧葡萄糖PET/CT检查，显示该病变具有恶性影像学特征，怀疑为神经淋巴瘤。活检证实了病变的性质。全身PET/CT未检测到其他恶性肿瘤部位。结论 外周神经的淋巴瘤累及在临床上可能与其他更常见的良性病症重叠；因此，尽管这种情况较为罕见，但对于有血液系统恶性肿瘤病史的患者，必须考虑到这种诊断。
