Tai Rebecca, Maingard Julian, Nambiar Mithun, Lim Kelvin
Department of Radiology, Austin Hospital, Heidelberg, Victoria, Australia.
Department of Radiology, The University of Melbourne, Parkville, Victoria, Australia.
BMJ Case Rep. 2019 Mar 6;12(3):e228742. doi: 10.1136/bcr-2018-228742.
Neurolymphomatosis (NL) is the infiltration of lymphocytes into the peripheral nervous system in a haematological malignancy. We describe the imaging features of NL in a patient with relapsed Burkitt-like non-Hodgkin's lymphoma on positron emission tomography (PET) and ultrasound. Imaging features on ultrasound are infrequently described and provide useful information in helping to establish an imaging diagnosis of NL. Features of NL in our patient included intense linear fluorodeoxyglucose-18 (FDG) uptake on PET along the affected median nerve. B-mode ultrasound demonstrated concentric tubular thickening and loss of fascicular architecture. Perineural and intraneural vascularity was present on colour Doppler ultrasound. It is important to be able to correlate ultrasound findings to features observed on FDG-PET as this aids in diagnosis and in guiding potential surgical biopsy.
神经淋巴瘤（NL）是血液系统恶性肿瘤中淋巴细胞浸润至周围神经系统。我们描述了1例复发的伯基特样非霍奇金淋巴瘤患者在正电子发射断层扫描（PET）和超声检查下NL的影像学特征。超声的影像学特征较少被描述，但在帮助建立NL的影像学诊断方面提供了有用信息。我们患者的NL特征包括PET上沿受累正中神经有强烈的线性氟脱氧葡萄糖-18（FDG）摄取。B型超声显示同心管状增厚和束状结构消失。彩色多普勒超声显示有神经周围和神经内血管。能够将超声检查结果与FDG-PET上观察到的特征相关联很重要，因为这有助于诊断并指导潜在的手术活检。
