Press G A, Weindling S M, Hesselink J R, Ochi J W, Harris J P
Department of Radiology, University of California, School of Medicine, San Diego 92103.
J Comput Assist Tomogr. 1988 Sep-Oct;12(5):744-9. doi: 10.1097/00004728-198809010-00005.
Magnetic resonance (MR) examinations of three patients with rhinocerebral mucormycosis are reviewed. The clinical course is outlined and the MR characteristics are analyzed in light of the known pathology. The major MR findings include sinus and orbital disease followed by deep facial extension. Involvement of basal portions of the hemispheres, brain stem, and hypothalamus occurred rapidly following ipsilateral facial or orbital invasion in all three cases. Regions of intracerebral inflammation were hyperintense compared with normal parenchyma on T2-weighted and proton density-weighted images. Septic cavernous sinus and internal carotid artery thrombosis was diagnosed by MR in one case. Magnetic resonance demonstrated partial resolution of intracerebral abnormalities that accompanied clinical improvement in the one surviving patient.
回顾了3例鼻脑型毛霉菌病患者的磁共振(MR)检查。概述了临床病程,并根据已知病理分析了MR特征。主要的MR表现包括鼻窦和眼眶疾病,随后是面部深部扩展。在所有3例病例中,同侧面部或眼眶侵犯后,半球基底部、脑干和下丘脑迅速受累。在T2加权和质子密度加权图像上,脑内炎症区域与正常实质相比呈高信号。1例通过MR诊断为感染性海绵窦和颈内动脉血栓形成。磁共振显示,1例存活患者脑内异常部分消退,同时临床症状改善。