Jontell M, Bergenholtz G, Scheynius A, Ambrose W
Department of Endodontics and Oral Diagnosis, Faculty of Odontology, University of Gothenburg, Sweden.
J Dent Res. 1988 Oct;67(10):1263-6. doi: 10.1177/00220345880670100301.
This study has identified and characterized class II (Ia) antigen-expressing cells in the normal rat incisor pulp by immunohistochemistry and flow cytometry. Two types of Ia-expressing cells occurred: one with a pronounced dendritic appearance located primarily in the periphery of the pulp, and one with morphological characteristics similar to those of macrophages. The latter cells were mainly observed in the central portion of the pulp. A numerical ratio of 1:4 was established between the two cell types. The existence of Ia-expressing cells suggests an inherent capacity of the pulp to process and present foreign antigens.
本研究通过免疫组织化学和流式细胞术鉴定并表征了正常大鼠切牙髓中表达II类（Ia）抗原的细胞。出现了两种类型的Ia表达细胞：一种具有明显的树突状外观，主要位于牙髓外周，另一种具有与巨噬细胞相似的形态特征。后一种细胞主要在牙髓中央部分观察到。两种细胞类型之间的数量比为1:4。Ia表达细胞的存在表明牙髓具有处理和呈递外来抗原的内在能力。
