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肥胖与接受剖腹手术的腹部创伤患者的预后不良相关:一项倾向评分匹配的全国性队列研究。

Obesity is Associated with Worse Outcomes Among Abdominal Trauma Patients Undergoing Laparotomy: A Propensity-Matched Nationwide Cohort Study.

机构信息

Department of Trauma and Burn Surgery, Stroger Hospital of Cook County, Rush University, 1950 West Polk Street, 8th floor, Chicago, IL, 60612, USA.

Department of Trauma and Emergency Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taoyüan, Taiwan.

出版信息

World J Surg. 2020 Mar;44(3):755-763. doi: 10.1007/s00268-019-05268-5.

Abstract

INTRODUCTION

Obesity is associated with increased morbidity and mortality in abdominal trauma patients. The characteristics of abdominal trauma patients with poor outcomes related to obesity require evaluation. We hypothesize that obesity is related to increased mortality and length of stay (LOS) among abdominal trauma patients undergoing laparotomies.

METHODS

Abdominal trauma patients were identified from the National Trauma Data Bank between 2013 and 2015. Patients who received laparotomies were analyzed using propensity score matching (PSM) to evaluate the mortality rate and LOS between obese and non-obese patients. Patients without laparotomies were analyzed as a control group using PSM cohort analysis.

RESULTS

A total of 33,798 abdominal trauma patients were evaluated, 10,987 of them received laparotomies. Of these patients, the proportion of obesity in deceased patients was significantly higher when compared to the survivors (33.1% vs. 26.2%, p < 0.001). Elevation of one kg/m of body mass index independently resulted in 2.5% increased odds of mortality. After a well-balanced PSM, obese patients undergoing laparotomies had significantly higher mortality rates [3.7% vs. 2.4%, standardized difference (SD) = 0.241], longer hospital LOS (11.1 vs. 9.6 days, SD = 0.135), and longer intensive care unit LOS (3.5 vs. 2.3 days, SD = 0.171) than non-obese patients undergoing laparotomies.

CONCLUSIONS

Obesity is associated with increased mortality in abdominal trauma patients who received laparotomies versus those who did not. Obesity requires a careful evaluation of alternatives to laparotomy in injured patients.

摘要

引言

肥胖与腹部创伤患者的发病率和死亡率增加有关。需要评估与肥胖相关的预后不良的腹部创伤患者的特征。我们假设肥胖与接受剖腹手术的腹部创伤患者的死亡率和住院时间(LOS)增加有关。

方法

从 2013 年至 2015 年,国家创伤数据库中确定了腹部创伤患者。使用倾向评分匹配(PSM)分析接受剖腹手术的患者,以评估肥胖患者和非肥胖患者的死亡率和 LOS。使用 PSM 队列分析对未接受剖腹手术的患者作为对照组进行分析。

结果

共评估了 33798 例腹部创伤患者,其中 10987 例接受了剖腹手术。在这些患者中,与幸存者相比,死亡患者中肥胖的比例明显更高(33.1%比 26.2%,p<0.001)。体重指数每增加 1kg/m,死亡率的几率就会增加 2.5%。经过良好平衡的 PSM 后,接受剖腹手术的肥胖患者的死亡率明显更高[3.7%比 2.4%,标准化差异(SD)=0.241],住院时间更长(11.1 天比 9.6 天,SD=0.135),重症监护病房时间更长(3.5 天比 2.3 天,SD=0.171)比未接受剖腹手术的非肥胖患者。

结论

与未接受剖腹手术的患者相比,接受剖腹手术的腹部创伤患者肥胖与死亡率增加相关。肥胖患者需要仔细评估替代剖腹手术的方法。

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