Department of Maternal and Child Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China.
Department of Public Health, Bao an Maternal and Child Health Hospital, Jinan University, Shenzhen, Guodong, China.
Sci Rep. 2019 Nov 12;9(1):16579. doi: 10.1038/s41598-019-53059-8.
Several studies have shown that dysmenorrhea increased the risk of depression. However, the association between dysmenorrhea and postpartum depression (PPD) is unclear. The purpose of this study is to evaluate the effects of dysmenorrhea on the development of PPD among Chinese women. A case-control study was performed on parturients who delivered from January 1, 2016, to December 31, 2016, at Bao an Maternal and Child Health Hospital in Shenzhen, China. The Edinburgh Postnatal Depression Scale (EPDS) was used to screen for maternal postpartum depression. Logistic regression models were used to examine the association between dysmenorrhea and the risk of PPD. A total of 360 women including 120 cases and 240 controls were enrolled. Our study showed that parturients with PPD had a higher percentage of dysmenorrhea than women without PPD (64.2% vs 47.9%, P = 0.004). In univariate analysis, we observed that dysmenorrhea increased the risk for PPD (OR = 1.95; 95% CI: 1.24-3.06; P = 0.004). In the fully adjusted model, dysmenorrhea was still significantly associated with an increased risk of PPD (OR = 2.45; 95% CI: 1.36-4.54; P = 0.003). Our data confirmed that dysmenorrhea may be a risk factor for PPD. Therefore, screening for postpartum depression should be considered in parturients with a history of dysmenorrhea.
几项研究表明,痛经会增加患抑郁症的风险。然而,痛经与产后抑郁症(PPD)之间的关系尚不清楚。本研究旨在评估痛经对中国妇女发生 PPD 的影响。我们对 2016 年 1 月 1 日至 12 月 31 日在深圳市宝安区妇幼保健院分娩的产妇进行了病例对照研究。采用爱丁堡产后抑郁量表(EPDS)筛查产妇产后抑郁。采用 logistic 回归模型检验痛经与 PPD 风险之间的关系。共纳入 360 名产妇,其中 120 例为病例组,240 例为对照组。我们的研究表明,患有 PPD 的产妇中痛经的比例高于无 PPD 的产妇(64.2%比 47.9%,P=0.004)。在单因素分析中,我们观察到痛经增加了 PPD 的风险(OR=1.95;95%CI:1.24-3.06;P=0.004)。在完全调整模型中,痛经与 PPD 的风险增加仍显著相关(OR=2.45;95%CI:1.36-4.54;P=0.003)。我们的数据证实痛经可能是 PPD 的一个危险因素。因此,对于有痛经病史的产妇,应考虑筛查产后抑郁症。