Iberdomide (CC-220) is a potent cereblon E3 ligase modulator with antitumor and immunostimulatory activities in lenalidomide- and pomalidomide-resistant multiple myeloma cells with dysregulated CRBN.
作者信息
Bjorklund Chad C, Kang Jian, Amatangelo Michael, Polonskaia Ann, Katz Mark, Chiu Hsiling, Couto Suzana, Wang Maria, Ren Yan, Ortiz Maria, Towfic Fadi, Flynt J Erin, Pierceall William, Thakurta Anjan
机构信息
Celgene Corporation, Summit, NJ, USA.
Celgene Corporation, San Diego, CA, USA.
出版信息
Leukemia. 2020 Apr;34(4):1197-1201. doi: 10.1038/s41375-019-0620-8. Epub 2019 Nov 12.
Abstract
摘要
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