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利福平诱发的一名结核病患者的肾毒性。

Rifampicin-induced nephrotoxicity in a tuberculosis patient.

作者信息

Beebe Alexandria, Seaworth Barbara, Patil Naveen

机构信息

Arkansas Department of Health, 4815 West Markham, Slot 45, Little Rock, AR 72205, United States.

University of Arkansas for Medical Sciences, 4301 West Markham, Little Rock, AR 72205, United States.

出版信息

J Clin Tuberc Other Mycobact Dis. 2015 Oct 24;1:13-15. doi: 10.1016/j.jctube.2015.09.001. eCollection 2015 Nov.

DOI:10.1016/j.jctube.2015.09.001
PMID:31723676
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6850238/
Abstract

Rifampicin is a widely used anti-tuberculosis agent. On rare occasions, the drug can cause adverse effects such as acute renal failure, though most regain complete renal function upon discontinuation of therapy. The following case report describes a 38 year old Hispanic male presenting with pulmonary tuberculosis who developed rifampicin-induced renal toxicity. He recovered renal function upon discontinuation of the medication without the use of corticosteroids.

摘要

利福平是一种广泛使用的抗结核药物。在极少数情况下,该药物可引起诸如急性肾衰竭等不良反应,不过大多数患者在停药后肾功能可完全恢复。以下病例报告描述了一名38岁的西班牙裔男性,患有肺结核,出现了利福平诱导的肾毒性。他在停药后未使用皮质类固醇的情况下恢复了肾功能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2955/6850238/4de256d36469/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2955/6850238/4de256d36469/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2955/6850238/4de256d36469/gr1.jpg

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J Res Med Sci. 2015 Apr;20(4):416-9.
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Rifampicin-induced acute kidney injury during the initial treatment for pulmonary tuberculosis: a case report and literature review.利福平在肺结核初始治疗期间所致急性肾损伤:一例病例报告及文献综述
Intern Med. 2013;52(21):2457-60. doi: 10.2169/internalmedicine.52.0634.
3
Rifampicin-associated acute renal failure and hemolysis: a rather uncommon but severe complication.利福平相关急性肾衰竭和溶血性贫血:一种相当不常见但严重的并发症。
伴有多器官合并感染的噬血细胞性淋巴组织细胞增生激活综合征:治疗困境
Kans J Med. 2023 Oct 30;16(3):268-270. doi: 10.17161/kjm.vol16.20957. eCollection 2023.
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Rifampicin-induced acute tubulointerstitial nephritis during pulmonary tuberculosis treatment: A case report.利福平诱发的急性肾小管间质性肾炎在肺结核治疗期间:一例报告。
Respirol Case Rep. 2023 Jul 17;11(8):e01190. doi: 10.1002/rcr2.1190. eCollection 2023 Aug.
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Protective Effects of Rifampicin and Its Analog Rifampicin Quinone in a Mouse Model of Obesity-Induced Type 2 Diabetes.利福平及其类似物醌式利福平在肥胖诱导的2型糖尿病小鼠模型中的保护作用
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