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利福平诱发的一名结核病患者的肾毒性。

Rifampicin-induced nephrotoxicity in a tuberculosis patient.

作者信息

Beebe Alexandria, Seaworth Barbara, Patil Naveen

机构信息

Arkansas Department of Health, 4815 West Markham, Slot 45, Little Rock, AR 72205, United States.

University of Arkansas for Medical Sciences, 4301 West Markham, Little Rock, AR 72205, United States.

出版信息

J Clin Tuberc Other Mycobact Dis. 2015 Oct 24;1:13-15. doi: 10.1016/j.jctube.2015.09.001. eCollection 2015 Nov.

Abstract

Rifampicin is a widely used anti-tuberculosis agent. On rare occasions, the drug can cause adverse effects such as acute renal failure, though most regain complete renal function upon discontinuation of therapy. The following case report describes a 38 year old Hispanic male presenting with pulmonary tuberculosis who developed rifampicin-induced renal toxicity. He recovered renal function upon discontinuation of the medication without the use of corticosteroids.

摘要

利福平是一种广泛使用的抗结核药物。在极少数情况下,该药物可引起诸如急性肾衰竭等不良反应,不过大多数患者在停药后肾功能可完全恢复。以下病例报告描述了一名38岁的西班牙裔男性,患有肺结核,出现了利福平诱导的肾毒性。他在停药后未使用皮质类固醇的情况下恢复了肾功能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2955/6850238/4de256d36469/gr1.jpg

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