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利福平诱发的急性肾小管间质性肾炎在肺结核治疗期间：一例报告。

Rifampicin-induced acute tubulointerstitial nephritis during pulmonary tuberculosis treatment: A case report.

作者信息

Moussa Chirine, Esbaa Samia, Rouis Houda, Sellami Nada, Hajji Meriam, Houcine Yoldez, Khattab Amel, Khouaja Ibtihel, Zendah Ines, Maâlej Sonia

机构信息

Pneumology Department 1 Abderrahmen Mami Hospital Ariana Tunisia.

Faculty of Medicine of Tunis El Manar University Tunis Tunisia.

出版信息

Respirol Case Rep. 2023 Jul 17;11(8):e01190. doi: 10.1002/rcr2.1190. eCollection 2023 Aug.

DOI:10.1002/rcr2.1190
PMID:37469571
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10352592/
Abstract

Drug-induced tubulointerstitial nephritis is an uncommon complication in patients on anti-tuberculosis therapy that can lead to permanent kidney damage. Rifampicin is the most offending drug. We report a case of a 41-years old man being treated for pulmonary tuberculosis and presenting with tubulointerstitial nephritis associated with rifampicin. We focus on diagnosis features and therapeutic challenges.

摘要

药物性肾小管间质性肾炎是抗结核治疗患者中一种罕见的并发症，可导致永久性肾损伤。利福平是最主要的致病药物。我们报告一例41岁男性患者，正在接受肺结核治疗，出现了与利福平相关的肾小管间质性肾炎。我们重点关注诊断特征和治疗挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77eb/10352592/f9c030687247/RCR2-11-e01190-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77eb/10352592/30f7c470bbd6/RCR2-11-e01190-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77eb/10352592/e7e1412a7aab/RCR2-11-e01190-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77eb/10352592/69652d86a9e4/RCR2-11-e01190-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77eb/10352592/f9c030687247/RCR2-11-e01190-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77eb/10352592/30f7c470bbd6/RCR2-11-e01190-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77eb/10352592/e7e1412a7aab/RCR2-11-e01190-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77eb/10352592/69652d86a9e4/RCR2-11-e01190-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77eb/10352592/f9c030687247/RCR2-11-e01190-g002.jpg

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本文引用的文献

1
Incidence of and Risk Factors for Acute Kidney Injury During Antituberculosis Treatment: A Prospective Cohort Study and Literature Review.抗结核治疗期间急性肾损伤的发生率及危险因素：一项前瞻性队列研究与文献综述
Infect Dis Ther. 2023 Mar;12(3):919-931. doi: 10.1007/s40121-023-00761-w. Epub 2023 Feb 11.
2
Rifampicin-induced nephrotoxicity in a tuberculosis patient.利福平诱发的一名结核病患者的肾毒性。
J Clin Tuberc Other Mycobact Dis. 2015 Oct 24;1:13-15. doi: 10.1016/j.jctube.2015.09.001. eCollection 2015 Nov.
3
A Case Series of Acute Kidney Injury During Anti-tuberculosis Treatment.
抗结核治疗期间急性肾损伤病例系列
Intern Med. 2019 Feb 15;58(4):521-527. doi: 10.2169/internalmedicine.0813-18. Epub 2018 Oct 17.
4
Successful management of acute interstitial nephritis in two cases of disseminated tuberculosis.两例播散性肺结核患者急性间质性肾炎的成功管理
Tuberculosis (Edinb). 2016 Dec;101S:S135-S136. doi: 10.1016/j.tube.2016.09.014. Epub 2016 Sep 28.
5
Biopsy-proven acute interstitial nephritis, 1993-2011: a case series.经活检证实的急性间质性肾炎，1993-2011 年：病例系列。
Am J Kidney Dis. 2014 Oct;64(4):558-66. doi: 10.1053/j.ajkd.2014.04.027. Epub 2014 Jun 11.
6
Acute kidney injury due to anti-tuberculosis drugs: a five-year experience in an aging population.抗结核药物导致的急性肾损伤：老龄化人群中的五年经验。
BMC Infect Dis. 2014 Jan 13;14:23. doi: 10.1186/1471-2334-14-23.
7
Rifampicin-induced acute kidney injury during the initial treatment for pulmonary tuberculosis: a case report and literature review.利福平在肺结核初始治疗期间所致急性肾损伤：一例病例报告及文献综述
Intern Med. 2013;52(21):2457-60. doi: 10.2169/internalmedicine.52.0634.
8
Drug-induced acute interstitial nephritis.药物性急性间质性肾炎。
Nat Rev Nephrol. 2010 Aug;6(8):461-70. doi: 10.1038/nrneph.2010.71. Epub 2010 Jun 1.