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利福平诱发的急性肾小管间质性肾炎在肺结核治疗期间:一例报告。

Rifampicin-induced acute tubulointerstitial nephritis during pulmonary tuberculosis treatment: A case report.

作者信息

Moussa Chirine, Esbaa Samia, Rouis Houda, Sellami Nada, Hajji Meriam, Houcine Yoldez, Khattab Amel, Khouaja Ibtihel, Zendah Ines, Maâlej Sonia

机构信息

Pneumology Department 1 Abderrahmen Mami Hospital Ariana Tunisia.

Faculty of Medicine of Tunis El Manar University Tunis Tunisia.

出版信息

Respirol Case Rep. 2023 Jul 17;11(8):e01190. doi: 10.1002/rcr2.1190. eCollection 2023 Aug.

Abstract

Drug-induced tubulointerstitial nephritis is an uncommon complication in patients on anti-tuberculosis therapy that can lead to permanent kidney damage. Rifampicin is the most offending drug. We report a case of a 41-years old man being treated for pulmonary tuberculosis and presenting with tubulointerstitial nephritis associated with rifampicin. We focus on diagnosis features and therapeutic challenges.

摘要

药物性肾小管间质性肾炎是抗结核治疗患者中一种罕见的并发症,可导致永久性肾损伤。利福平是最主要的致病药物。我们报告一例41岁男性患者,正在接受肺结核治疗,出现了与利福平相关的肾小管间质性肾炎。我们重点关注诊断特征和治疗挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77eb/10352592/30f7c470bbd6/RCR2-11-e01190-g005.jpg

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