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1
Rifampicin-Induced Nephrotoxicity in a Tuberculosis Patient: Treatment Dilemma?利福平诱发的结核病患者肾毒性：治疗困境？
Eur J Case Rep Intern Med. 2021 Oct 14;8(10):002833. doi: 10.12890/2021_002833. eCollection 2021.
2
Severe acute renal failure due to tubulointerstitial nephritis, pancreatitis, and hyperthyroidism in a patient during rifampicin therapy.
Adv Ther. 2005 May-Jun;22(3):241-3. doi: 10.1007/BF02849933.
3
Rifampicin-induced acute tubulointerstitial nephritis during pulmonary tuberculosis treatment: A case report.利福平诱发的急性肾小管间质性肾炎在肺结核治疗期间：一例报告。
Respirol Case Rep. 2023 Jul 17;11(8):e01190. doi: 10.1002/rcr2.1190. eCollection 2023 Aug.
4
Acute tubulo-interstitial nephritis requiring dialysis associated with intermittent rifampicin use: case report.与间歇性使用利福平相关的需要透析的急性肾小管间质性肾炎：病例报告
Int J Artif Organs. 1999 Jul;22(7):477-81.
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Rifampicin-induced acute kidney injury during the initial treatment for pulmonary tuberculosis: a case report and literature review.利福平在肺结核初始治疗期间所致急性肾损伤：一例病例报告及文献综述
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Acute rifampicin-associated interstitial tubulopathy in a patient with pulmonary tuberculosis: a case report.一名肺结核患者发生的急性利福平相关性间质性肾小管病：病例报告
J Med Case Rep. 2013 Apr 17;7:106. doi: 10.1186/1752-1947-7-106.
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Rifampicin-associated acute renal failure and hemolysis: a rather uncommon but severe complication.利福平相关急性肾衰竭和溶血性贫血：一种相当不常见但严重的并发症。
Ren Fail. 2013 Sep;35(8):1179-81. doi: 10.3109/0886022X.2013.815567. Epub 2013 Jul 25.
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Crescentic glomerulonephritis associated with rifampicin in a patient co-infected with tuberculosis and human immunodeficiency virus.一名同时感染结核和人类免疫缺陷病毒的患者中与利福平相关的新月体性肾小球肾炎
Clin Nephrol. 2006 Apr;65(4):284-9. doi: 10.5414/cnp65284.
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A Case Series of Acute Kidney Injury During Anti-tuberculosis Treatment.抗结核治疗期间急性肾损伤病例系列
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Minimal change disease related to rifampicin presenting with acute renal failure during treatment for latent tuberculosis infection: A case report.利福平相关微小病变病在潜伏性结核感染治疗期间伴发急性肾衰竭：一例报告
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引用本文的文献

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Clinical standards for the management of adverse effects during treatment for TB.肺结核治疗过程中不良反应管理的临床标准。
Int J Tuberc Lung Dis. 2023 Jul 1;27(7):506-519. doi: 10.5588/ijtld.23.0078.

本文引用的文献

1
Rifampicin-induced nephrotoxicity in a tuberculosis patient.利福平诱发的一名结核病患者的肾毒性。
J Clin Tuberc Other Mycobact Dis. 2015 Oct 24;1:13-15. doi: 10.1016/j.jctube.2015.09.001. eCollection 2015 Nov.
2
Tubulointerstitial nephritis: diagnosis, treatment, and monitoring.肾小管间质性肾炎：诊断、治疗与监测
Pediatr Nephrol. 2017 Apr;32(4):577-587. doi: 10.1007/s00467-016-3394-5. Epub 2016 May 7.
3
Rifampicin-associated acute renal failure and hemolysis: a rather uncommon but severe complication.利福平相关急性肾衰竭和溶血性贫血：一种相当不常见但严重的并发症。
Ren Fail. 2013 Sep;35(8):1179-81. doi: 10.3109/0886022X.2013.815567. Epub 2013 Jul 25.
4
Early steroid treatment improves the recovery of renal function in patients with drug-induced acute interstitial nephritis.早期使用类固醇治疗可改善药物性急性间质性肾炎患者的肾功能恢复情况。
Kidney Int. 2008 Apr;73(8):940-6. doi: 10.1038/sj.ki.5002776. Epub 2008 Jan 9.
5
Acute interstitial nephritis: clinical features and response to corticosteroid therapy.急性间质性肾炎：临床特征及对皮质类固醇治疗的反应
Nephrol Dial Transplant. 2004 Nov;19(11):2778-83. doi: 10.1093/ndt/gfh485. Epub 2004 Aug 31.

利福平诱发的结核病患者肾毒性：治疗困境？

Rifampicin-Induced Nephrotoxicity in a Tuberculosis Patient: Treatment Dilemma?

作者信息

Grilo Novais António, Silva Cláudio, Coelho Ana Rita, Silva Roberto, Carvalho Ana Cláudia

机构信息

Internal Medicine Department, Centro Hospitalar Tondela-Viseu, E.P.E, Portugal.

Infectious Diseases Department, Centro Hospitalar Universitário São João, Porto, Portugal.

出版信息

Eur J Case Rep Intern Med. 2021 Oct 14;8(10):002833. doi: 10.12890/2021_002833. eCollection 2021.

DOI:10.12890/2021_002833
PMID:34790626
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8592655/
Abstract

UNLABELLED

Acute kidney injury related to rifampin is usually a clinical diagnosis. We report a case of a man being treated for pulmonary tuberculosis with acute tubulointerstitial nephritis related to rifampicin.

LEARNING POINTS

Rifampicin can cause acute kidney injury.Renal impairment may develop weeks after rifampicin administration was started.

摘要

未标注

与利福平相关的急性肾损伤通常是临床诊断。我们报告一例正在接受肺结核治疗的男性患者，发生了与利福平相关的急性肾小管间质性肾炎。

学习要点

利福平可导致急性肾损伤。肾损害可能在开始使用利福平数周后出现。