Pensel J, Sommer K, Thomas S, Lieck P, Baretton G
Medical Laser Center, Medical University Lübeck, Federal Republic of Germany.
Lasers Surg Med. 1988;8(4):371-6. doi: 10.1002/lsm.1900080406.
Current development in endourologic equipment has made possible the endoscopic application of the Nd:YAG laser in the treatment of urothelial tumors of the whole urinary tract. The clinical results are rather promising. We controlled with various methods the healing processes of 14 rabbit ureters after Nd:YAG laser treatment as to morphological repair and physiological function. The ureters were irradiated transrenally with an energy of 60 J coagulating all wall layers. Healing of the laser lesions nearly to normal in all animals was observed 4 to 6 weeks after treatment. The prevailing histological and physiological changes in the ureter are extremely slight and do not disturb the normal ureteral function. The results show the complete healing process of the ureter after laser coagulation and make the application of Nd:YAG laser in the upper urinary tract much more predictable.
目前腔内泌尿外科设备的发展使得钕钇铝石榴石（Nd:YAG）激光在内镜下应用于治疗全尿路尿路上皮肿瘤成为可能。临床结果相当令人鼓舞。我们用各种方法控制了14只兔子输尿管在接受Nd:YAG激光治疗后的愈合过程，包括形态修复和生理功能。通过经肾以60焦耳的能量照射输尿管，使各壁层均发生凝固。治疗后4至6周观察到所有动物的激光损伤几乎完全愈合至正常状态。输尿管中主要的组织学和生理学变化极其轻微，并未干扰输尿管的正常功能。结果显示了激光凝固后输尿管的完全愈合过程，并使Nd:YAG激光在上尿路的应用更具可预测性。
