Van Stiegmann G, Sun J H, Pearlman N W, Hammond W S
Department of Surgery, University of Colorado Health Sciences Center, Denver 80262.
Lasers Surg Med. 1988;8(4):409-12. doi: 10.1002/lsm.1900080412.
A nonlight-transmitting contact laser probe was used to treat acutely bleeding gastric ulcers in heparinized dogs. Thirty-five treated ulcers responded with complete hemostasis following 21-92 seconds (mean, 32 seconds) application per ulcer. Ten control ulcers left untreated bled for 5-30 minutes (mean, 11 minutes). Hemostasis was maintained at treated sites for the entire observation period (60 minutes). Perforations did not occur, and there was no evidence of full thickness injury. Histological assessment confirmed a limited (0.2-0.5 mm) zone of coagulation injury. The laser probe is effective for control of acute bleeding in this canine ulcer model.
使用一种不透光的接触式激光探头治疗肝素化犬的急性出血性胃溃疡。35个接受治疗的溃疡在每个溃疡应用21 - 92秒(平均32秒)后实现完全止血。10个未治疗的对照溃疡出血5 - 30分钟(平均11分钟)。在整个观察期(60分钟)内,治疗部位均保持止血状态。未发生穿孔,也没有全层损伤的证据。组织学评估证实存在有限的(0.2 - 0.5毫米)凝固性损伤区域。该激光探头在这种犬类溃疡模型中对控制急性出血有效。