男性原发性骨质疏松症：未满足的医学需求。

Primary osteoporosis in men: an unmet medical need.

机构信息

Division of Rheumatology, Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania; Jefferson Institute of Molecular Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania.

Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania.

出版信息

Fertil Steril. 2019 Nov;112(5):791-798. doi: 10.1016/j.fertnstert.2019.10.003.

DOI:10.1016/j.fertnstert.2019.10.003

PMID:31731933

Abstract

Osteoporosis is a skeletal disease characterized by loss of bone strength and increased risk of fractures. Even though fracture prevalence is higher in women, fractures also constitute a significant public health issue in older men. Men are screened less and more frequently undertreated than female patients. It is the goal of this review, to summarize updated information about the current understanding of pathophysiology and clinical aspects of diagnosis and treatment of osteoporosis in men.

摘要

骨质疏松症是一种骨骼疾病，其特征是骨强度丧失和骨折风险增加。尽管女性骨折的患病率更高，但老年人中男性骨折也是一个重大的公共卫生问题。男性接受筛查的频率较低，且治疗不足的情况更为常见。本文旨在总结有关男性骨质疏松症的病理生理学和临床诊断及治疗方面的最新认识。