Ichinari Daisuke, Ashikari Yosuke, Mandai Kyoko, Aizawa Yoko, Yoshida Jun-Ichi, Nagaki Aiichiro
Department of Synthetic and Biological Chemistry, Graduate School of Engineering, Kyoto University, Nishikyo-ku, Kyoto, 615-8510, Japan.
National Institute of Technology, Suzuka College, Shiroko-cho, Suzuka, Mie, 510-0294, Japan.
Angew Chem Int Ed Engl. 2020 Jan 20;59(4):1567-1571. doi: 10.1002/anie.201912419. Epub 2019 Dec 6.
A novel straightforward method for aryl azides having functional groups based on generation and reactions of aryllithiums bearing a triazene group from polybromoarenes using flow microreactor systems was achieved. The present approach will serve as a powerful method in organolithium chemistry and open a new possibility in the synthesis of polyfunctional organic azides.
基于使用流动微反应器系统从多溴芳烃生成带有三氮烯基团的芳基锂并进行反应，实现了一种用于具有官能团的芳基叠氮化物的新颖直接方法。本方法将成为有机锂化学中的一种强大方法，并为多官能团有机叠氮化物的合成开辟新的可能性。
