College of Science, Sichuan Agricultural University, Xin Kang Road, Yucheng District, Ya'an, 625014, People's Republic of China.
College of Information Engineering, Sichuan Agricultural University, Xin Kang Road, Yucheng District, Ya'an, 625014, People's Republic of China.
Mikrochim Acta. 2019 Nov 16;186(12):795. doi: 10.1007/s00604-019-3907-6.
A glassy carbon electrode (GCE) was modified with nitrogen-enriched carbon frameworks decorated with palladium nanoparticles (Pd@NCF/GCEs). The modified GCE is shown to be a viable tool for determination of uric acid (UA) and dopamine (DA) in the presence of ascorbic acid (AA). The Pd@NCF was fabricated though one-step pyrolysis and characterized by X-ray photoelectron spectroscopy, X-ray diffraction, scanning electron microscopy and nitrogen-adsorption/desorption analysis. The Pd@NCF/GCE was characterized by differential pulse voltammetry (DPV). Both UA and DA have pronounced oxidation peaks (at 360 mV for UA and 180 mV for DA, all vs. Ag/AgCl) in the presence of AA. Response is linear in the 0.5-100 μM UA concentration range and in the 0.5-230 μM DA concentration range. The detection limits are 76 and 107 nM, respectively (at S/N = 3). This electrode is stable, reproducible and highly selective. It was used for UA and DA determination in spiked serum samples. Graphical abstractSchematic representation of nitrogen-enriched carbon frameworks decorated with palladium nanoparticles co-modified glassy carbon electrode for simultaneous determination of dopamine and uric acid in the presence of ascorbic acid.
玻碳电极（GCE）用富含氮的碳框架修饰，碳框架上装饰有钯纳米粒子（Pd@NCF/GCEs）。该修饰的 GCE 被证明是一种可行的工具，可用于在抗坏血酸（AA）存在的情况下测定尿酸（UA）和多巴胺（DA）。Pd@NCF 通过一步热解制备，并通过 X 射线光电子能谱、X 射线衍射、扫描电子显微镜和氮吸附/解吸分析进行了表征。Pd@NCF/GCE 通过差分脉冲伏安法（DPV）进行了表征。在 AA 存在的情况下，UA 和 DA 都具有明显的氧化峰（UA 的氧化峰在 360 mV，DA 的氧化峰在 180 mV，均相对于 Ag/AgCl）。在 0.5-100 μM UA 浓度范围内和 0.5-230 μM DA 浓度范围内，响应呈线性。检测限分别为 76 和 107 nM（S/N=3）。该电极稳定、重现性好且选择性高。它被用于测定加标血清样品中的 UA 和 DA。
