• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Crystal structures of N-terminal WRKY transcription factors and DNA complexes.

作者信息

Xu Yong-Ping, Xu Hua, Wang Bo, Su Xiao-Dong

机构信息

State Key Laboratory of Protein and Plant Gene Research, and Biomedical Pioneering Innovation Center (BIOPIC), Peking University, Beijing, 100871, China.

出版信息

Protein Cell. 2020 Mar;11(3):208-213. doi: 10.1007/s13238-019-00670-0.

DOI:10.1007/s13238-019-00670-0
PMID:31734872
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7026264/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86a2/7026347/4206a4eb1e7b/13238_2019_670_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86a2/7026347/f78b32d37517/13238_2019_670_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86a2/7026347/4206a4eb1e7b/13238_2019_670_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86a2/7026347/f78b32d37517/13238_2019_670_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86a2/7026347/4206a4eb1e7b/13238_2019_670_Fig2_HTML.jpg

相似文献

1
Crystal structures of N-terminal WRKY transcription factors and DNA complexes.N端WRKY转录因子与DNA复合物的晶体结构
Protein Cell. 2020 Mar;11(3):208-213. doi: 10.1007/s13238-019-00670-0.
2
Crystallization and preliminary X-ray analysis of the C-terminal WRKY domain of Arabidopsis thaliana WRKY1 transcription factor.拟南芥WRKY1转录因子C端WRKY结构域的结晶及初步X射线分析
Biochim Biophys Acta. 2005 Jun 15;1750(1):14-6. doi: 10.1016/j.bbapap.2005.03.013. Epub 2005 Apr 13.
3
Crystal structure of Arabidopsis thaliana calmodulin7 and insight into its mode of DNA binding.拟南芥钙调蛋白7的晶体结构及其DNA结合模式解析
FEBS Lett. 2016 Sep;590(17):3029-39. doi: 10.1002/1873-3468.12349. Epub 2016 Aug 24.
4
DNA binding mechanism revealed by high resolution crystal structure of Arabidopsis thaliana WRKY1 protein.拟南芥WRKY1蛋白高分辨率晶体结构揭示的DNA结合机制
Nucleic Acids Res. 2007;35(4):1145-54. doi: 10.1093/nar/gkm001. Epub 2007 Jan 30.
5
Structural basis for sequence-specific DNA recognition by an Arabidopsis WRKY transcription factor.拟南芥 WRKY 转录因子序列特异性 DNA 识别的结构基础。
J Biol Chem. 2012 Mar 2;287(10):7683-91. doi: 10.1074/jbc.M111.279844. Epub 2012 Jan 4.
6
Solution structure of the major DNA-binding domain of Arabidopsis thaliana ethylene-insensitive3-like3.拟南芥乙烯不敏感3样蛋白3主要DNA结合结构域的溶液结构
J Mol Biol. 2005 Apr 29;348(2):253-64. doi: 10.1016/j.jmb.2005.02.065.
7
Crystal Structure of the Arabidopsis thaliana L1L/NF-YC3 Histone-fold Dimer Reveals Specificities of the LEC1 Family of NF-Y Subunits in Plants.拟南芥L1L/NF-YC3组蛋白折叠二聚体的晶体结构揭示了植物中NF-Y亚基LEC1家族的特异性。
Mol Plant. 2017 Apr 3;10(4):645-648. doi: 10.1016/j.molp.2016.11.006. Epub 2016 Nov 18.
8
A novel zinc-binding motif revealed by solution structures of DNA-binding domains of Arabidopsis SBP-family transcription factors.拟南芥SBP家族转录因子DNA结合结构域的溶液结构揭示的一种新型锌结合基序。
J Mol Biol. 2004 Mar 12;337(1):49-63. doi: 10.1016/j.jmb.2004.01.015.
9
Biochemical and Structural Insights into the Mechanism of DNA Recognition by Arabidopsis ETHYLENE INSENSITIVE3.拟南芥乙烯不敏感3蛋白识别DNA机制的生化与结构解析
PLoS One. 2015 Sep 9;10(9):e0137439. doi: 10.1371/journal.pone.0137439. eCollection 2015.
10
DNA binding by the plant-specific NAC transcription factors in crystal and solution: a firm link to WRKY and GCM transcription factors.植物特异性 NAC 转录因子在晶体和溶液中的 DNA 结合:与 WRKY 和 GCM 转录因子的紧密联系。
Biochem J. 2012 Jun 15;444(3):395-404. doi: 10.1042/BJ20111742.

引用本文的文献

1
stimulates thermotolerance in potato ( L.) through antioxidant and photosynthetic modulation.通过抗氧化和光合调节提高马铃薯的耐热性。
Front Plant Sci. 2025 Jul 21;16:1634338. doi: 10.3389/fpls.2025.1634338. eCollection 2025.
2
The transcription factor WRKY25 can act as redox switch to drive the expression of WRKY53 during leaf senescence in arabidopsis.转录因子WRKY25可作为氧化还原开关,在拟南芥叶片衰老过程中驱动WRKY53的表达。
Sci Rep. 2025 Jul 29;15(1):27623. doi: 10.1038/s41598-025-13023-1.
3
DNA-Protein Binding is Dominated by Short Anchoring Elements.

本文引用的文献

1
Structural basis of dimerization and dual W-box DNA recognition by rice WRKY domain.水稻 WRKY 结构域二聚化和双 W 框 DNA 识别的结构基础。
Nucleic Acids Res. 2019 May 7;47(8):4308-4318. doi: 10.1093/nar/gkz113.
2
Transcription factor ThWRKY4 binds to a novel WLS motif and a RAV1A element in addition to the W-box to regulate gene expression.转录因子 ThWRKY4 除了 W 框之外,还与一个新的 WLS 基序和 RAV1A 元件结合,以调节基因表达。
Plant Sci. 2017 Aug;261:38-49. doi: 10.1016/j.plantsci.2017.04.016. Epub 2017 May 4.
3
WRKY1 regulates stomatal movement in drought-stressed Arabidopsis thaliana.
DNA与蛋白质的结合主要由短锚定元件主导。
Adv Sci (Weinh). 2025 May;12(19):e2414823. doi: 10.1002/advs.202414823. Epub 2025 Mar 26.
4
Multisite λ-Dynamics for Protein-DNA Binding Affinity Prediction.用于蛋白质 - DNA 结合亲和力预测的多位点 λ 动力学
J Chem Theory Comput. 2025 Apr 8;21(7):3536-3544. doi: 10.1021/acs.jctc.4c01408. Epub 2025 Mar 24.
5
WRKY36-PIL15 Transcription Factor Complex Negatively Regulates Sheath Blight Resistance and Seed Development in Rice.WRKY36-PIL15转录因子复合物负向调控水稻纹枯病抗性和种子发育
Plants (Basel). 2025 Feb 8;14(4):518. doi: 10.3390/plants14040518.
6
Protein target search diffusion-association/dissociation free energy landscape around DNA binding site with flanking sequences.蛋白质靶点搜索:围绕具有侧翼序列的DNA结合位点的扩散-缔合/解离自由能景观。
Biophys J. 2025 Feb 18;124(4):677-692. doi: 10.1016/j.bpj.2025.01.005. Epub 2025 Jan 16.
7
Structural basis for the regulation of plant transcription factor WRKY33 by the VQ protein SIB1.植物转录因子 WRKY33 受 VQ 蛋白 SIB1 调控的结构基础。
Commun Biol. 2024 May 11;7(1):561. doi: 10.1038/s42003-024-06258-7.
8
Unmasking the invaders: NLR-mal function in plant defense.揭开入侵者的面纱:植物防御中的NLR功能异常
Front Plant Sci. 2023 Nov 20;14:1307294. doi: 10.3389/fpls.2023.1307294. eCollection 2023.
9
Nonspecific vs. specific DNA binding free energetics of a transcription factor domain protein.转录因子结构域蛋白的非特异性与特异性 DNA 结合自由能。
Biophys J. 2023 Nov 21;122(22):4476-4487. doi: 10.1016/j.bpj.2023.10.025. Epub 2023 Oct 29.
10
KaScape: a sequencing-based method for global characterization of protein‒DNA binding affinity.KaScape:一种基于测序的蛋白质-DNA结合亲和力全局表征方法。
Sci Rep. 2023 Oct 3;13(1):16595. doi: 10.1038/s41598-023-43426-x.
WRKY1调控干旱胁迫下拟南芥的气孔运动。
Plant Mol Biol. 2016 May;91(1-2):53-65. doi: 10.1007/s11103-016-0441-3. Epub 2016 Jan 28.
4
Elucidating the evolutionary conserved DNA-binding specificities of WRKY transcription factors by molecular dynamics and in vitro binding assays.通过分子动力学和体外结合实验阐明 WRKY 转录因子的进化保守的 DNA 结合特异性。
Nucleic Acids Res. 2013 Nov;41(21):9764-78. doi: 10.1093/nar/gkt732. Epub 2013 Aug 23.
5
Structural basis for sequence-specific DNA recognition by an Arabidopsis WRKY transcription factor.拟南芥 WRKY 转录因子序列特异性 DNA 识别的结构基础。
J Biol Chem. 2012 Mar 2;287(10):7683-91. doi: 10.1074/jbc.M111.279844. Epub 2012 Jan 4.
6
WRKY: its structure, evolutionary relationship, DNA-binding selectivity, role in stress tolerance and development of plants.WRKY:其结构、进化关系、DNA 结合选择性、在植物耐逆性和发育中的作用。
Mol Biol Rep. 2011 Aug;38(6):3883-96. doi: 10.1007/s11033-010-0504-5. Epub 2010 Nov 25.
7
Studies on DNA-binding selectivity of WRKY transcription factors lend structural clues into WRKY-domain function.关于WRKY转录因子DNA结合选择性的研究为WRKY结构域功能提供了结构线索。
Plant Mol Biol. 2008 Sep;68(1-2):81-92. doi: 10.1007/s11103-008-9353-1. Epub 2008 Jun 4.
8
DNA binding mechanism revealed by high resolution crystal structure of Arabidopsis thaliana WRKY1 protein.拟南芥WRKY1蛋白高分辨率晶体结构揭示的DNA结合机制
Nucleic Acids Res. 2007;35(4):1145-54. doi: 10.1093/nar/gkm001. Epub 2007 Jan 30.
9
Solution structure of an Arabidopsis WRKY DNA binding domain.拟南芥WRKY DNA结合结构域的溶液结构
Plant Cell. 2005 Mar;17(3):944-56. doi: 10.1105/tpc.104.026435. Epub 2005 Feb 10.
10
WRKY transcription factors: from DNA binding towards biological function.WRKY转录因子:从DNA结合到生物学功能
Curr Opin Plant Biol. 2004 Oct;7(5):491-8. doi: 10.1016/j.pbi.2004.07.012.