Zhang Sophia, Khosravi Hasan, Cardis Michael, Jedrych Jaroslaw, Ho Jonhan, Bunimovich Yuri
University of Pittsburgh School of Medicine, Pittsburgh, PA.
Dermatol Online J. 2019 Oct 15;25(10):13030/qt0z03z1bj.
We report a patient with penile sarcomatoid squamous cell carcinoma (SCC) initially misdiagnosed as condyloma acuminatum. Sarcomatoid SCC is a rare, aggressive, biphasic cancer that often presents a diagnostic challenge and carries a poor prognosis, especially after a delay in diagnosis. Although sarcomatoid SCC may exhibit a broad range of clinical features, the expression of p63 and keratin 34?E12 is a common finding. Our case highlights the importance of accurate clinicopathologic correlation to facilitate a timely diagnosis and management of this rare and highly aggressive malignancy.
我们报告了一名阴茎肉瘤样鳞状细胞癌（SCC）患者，最初被误诊为尖锐湿疣。肉瘤样SCC是一种罕见、侵袭性、具有双相性的癌症，常常带来诊断挑战且预后不良，尤其是在诊断延迟之后。尽管肉瘤样SCC可能表现出广泛的临床特征，但p63和角蛋白34βE12的表达是常见表现。我们的病例强调了准确的临床病理相关性对于及时诊断和处理这种罕见且高度侵袭性恶性肿瘤的重要性。
