Wade T R, Kopf A W, Ackerman A B
Cancer. 1978 Oct;42(4):1890-903. doi: 10.1002/1097-0142(197810)42:4<1890::aid-cncr2820420430>3.0.co;2-c.
During the past 18 months we have studied 36 biopsy specimens taken from 11 young men ranging in age from 21 to 36, each of whom had multiple, reddish to violaceous papules, some distinctly verrucoid or velvety on either or both the shaft and glans of the penis. The clinical diagnoses accompanying the biopsy specimens were lichen planus, psoriasis and condyloma acuminatum. In no instance was carcinomia in situ suggested in the differential diagnosis. Histologically, however, all specimens submitted showed indubitable changes of squamous cell carcinoma in situ.
在过去的18个月里，我们研究了从11名年龄在21岁至36岁之间的年轻男性身上获取的36份活检标本，他们每个人的阴茎体部和龟头均有多个淡红色至紫蓝色丘疹，有些明显呈疣状或天鹅绒样。送检活检标本时的临床诊断为扁平苔藓、银屑病和尖锐湿疣。在鉴别诊断中均未提示原位癌。然而，组织学检查显示，所有送检标本均有明确的原位鳞状细胞癌改变。
