Yoshida Michihiro, Naitoh Itaru, Hayashi Kazuki, Jinno Naruomi, Natsume Makoto, Hori Yasuki, Kato Akihisa, Kachi Kenta, Asano Go, Matsuo Yoichi, Takahashi Satoru, Kataoka Hiromi
Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Japan.
Department of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences, Japan.
Intern Med. 2020 Mar 1;59(5):649-656. doi: 10.2169/internalmedicine.3912-19. Epub 2019 Nov 18.
Pancreatic serous cystic neoplasms (SCNs), such as serous cystadenoma (SCA), are generally recognized as benign because malignant counterparts of SCNs have been extremely rare. In clinical practice, pancreatic cystic neoplasms diagnosed as SCNs have been managed by conservative observation, as long as the patients remained asymptomatic. We herein report a case of metachronous ductal adenocarcinoma that was discovered during long-term follow-up of SCN and review the related literature. To our knowledge, this was the first reported case of the local presence of ductal adenocarcinoma adjacent to SCA that was preoperatively diagnosed by endoscopic ultrasound-guided fine-needle aspiration.
胰腺浆液性囊性肿瘤（SCNs），如浆液性囊腺瘤（SCA），通常被认为是良性的，因为SCNs的恶性对应物极为罕见。在临床实践中，诊断为SCNs的胰腺囊性肿瘤一直通过保守观察来处理，只要患者没有症状。我们在此报告一例在SCN的长期随访中发现的异时性导管腺癌病例，并回顾相关文献。据我们所知，这是第一例经内镜超声引导下细针穿刺术前诊断出的与SCA相邻的局部导管腺癌病例。
