Multi-modality Medical Imaging (M3I) group, Faculty of Science and Technology, Technical Medical Centre, University of Twente, Enschede, the Netherlands.
Department of Vascular Surgery, Medisch Spectrum Twente, Enschede, the Netherlands.
J Endovasc Ther. 2019 Dec;26(6):855-864. doi: 10.1177/1526602819882379.
To evaluate if the radial force of the double sealing ring of the Anaconda stent-graft induces dilatation in the perirenal aortic neck adjacent to the rings. This study evaluated the serial electrocardiogram-gated computed tomography scans of 15 abdominal aortic aneurysm patients (mean age 72.8±3.7 years; 14 men) who were treated electively using an Anaconda stent-graft. Follow-up scans were conducted before discharge and at 1, 6, 12, and 24 months after endovascular repair. Diameter and area were assessed perpendicular to the aortic centerline along the perirenal aortic neck, which was subdivided into 3 zones: the suprastent, the stent, and the infrastent zones. Measurements were performed independently by 2 experienced observers using dedicated 3-dimensional image processing software. Between discharge and the 2-year follow-up the diameter and area remained stable in the suprastent zone [average diameter change: -0.1±0.4 mm (-0.4%±1.7%), p=0.893; average area change: -2.9±17.2 mm (-0.7%±3.4%), p=0.946], increased in the stent zone [average diameter change: +1.9±1.0 mm (+7.3%±4.0%), p<0.001; average area change: +84.3±48.3 mm (+15.5%±8.7%), p<0.001], and diverged in the infrastent zone [average diameter change: -0.8±2.2 mm (-2.3%±7.4%), p>0.99; average area change: -34.6±102.3 mm (-4.1%±14.8%), p>0.99; increased in 4 patients, decreased in 9 patients]. After Anaconda implantation the infrarenal aortic neck accommodated to the expansion of the sealing rings at the stent zone. Below the stent zone the neck diameter decreased in the majority of patients, while an increase was related to downstream displacement of the main body. A decrease in size in the infrastent zone may contribute to durable sealing and fixation. A personalized follow-up scheme based on geometric neck remodeling should be feasible if our observations are confirmed in larger, long-term studies.
评估 Anaconda 覆膜支架双密封圈的径向力是否会导致毗邻密封圈的肾周主动脉颈扩张。本研究对 15 例接受 Anaconda 覆膜支架腔内修复的腹主动脉瘤患者(平均年龄 72.8±3.7 岁;14 名男性)的连续心电图门控计算机断层扫描进行了评估。在出院前和血管内修复后 1、6、12 和 24 个月进行了随访扫描。使用专用的 3 维图像处理软件,在垂直于主动脉中心线的肾周主动脉颈处评估直径和面积,将其分为 3 个区:支架上区、支架区和支架下区。由 2 名经验丰富的观察者独立进行测量。从出院到 2 年随访期间,支架上区的直径和面积保持稳定[平均直径变化:-0.1±0.4mm(-0.4%±1.7%),p=0.893;平均面积变化:-2.9±17.2mm(-0.7%±3.4%),p=0.946],支架区的直径和面积增加[平均直径变化:+1.9±1.0mm(+7.3%±4.0%),p<0.001;平均面积变化:+84.3±48.3mm(+15.5%±8.7%),p<0.001],支架下区的直径和面积发散[平均直径变化:-0.8±2.2mm(-2.3%±7.4%),p>0.99;平均面积变化:-34.6±102.3mm(-4.1%±14.8%),p>0.99;4 例患者增加,9 例患者减少]。Anaconda 植入后,肾下主动脉颈适应支架区密封圈的扩张。在支架区以下,大多数患者的颈部直径减小,而直径增加与主体的下游移位有关。支架下区的尺寸减小可能有助于持久的密封和固定。如果我们的观察结果在更大、长期的研究中得到证实,基于几何颈部重塑的个性化随访方案应该是可行的。