Meneses Liane, Santos Filipa, Gameiro Ana Rita, Paiva Alexandre, Duarte Ana Rita C
LAQV, REQUIMTE, Departamento de Química da Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa.
LAQV, REQUIMTE, Departamento de Química da Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa;
J Vis Exp. 2019 Oct 31(152). doi: 10.3791/60326.
The preparation of deep eutectic systems (DES) is a priori a simple procedure. By definition, two or more components are mixed together at a given molar ratio to form a DES. However, from our experience in the laboratory, there is a need to standardize the procedure to prepare, characterize and report the methodologies followed by different researchers, so that the results published can be reproduced. In this work, we test different approaches reported in the literature to prepare eutectic systems and evaluated the importance of water in the successful preparation of liquid systems at room temperature. These published eutectic systems were composed of citric acid, glucose, sucrose, malic acid, β-alanine, L-tartaric acid and betaine and not all of preparation methods described could be reproduced. However, in some cases, it was possible to reproduce the systems described, with the inclusion of water as a third component of the eutectic mixture.
深共熔体系（DES）的制备原则上是一个简单的过程。根据定义，将两种或更多种组分按给定的摩尔比混合在一起以形成深共熔体系。然而，根据我们在实验室的经验，有必要规范制备、表征和报告不同研究人员所采用方法的程序，以便已发表的结果能够被重现。在这项工作中，我们测试了文献中报道的制备共熔体系的不同方法，并评估了水在室温下成功制备液体体系中的重要性。这些已发表的共熔体系由柠檬酸、葡萄糖、蔗糖、苹果酸、β-丙氨酸、L-酒石酸和甜菜碱组成，并非所有描述的制备方法都能被重现。然而，在某些情况下，通过将水作为共熔混合物的第三种组分加入，可以重现所描述的体系。
