Elisevich K, Ciriello J
Department of Physiology, University of Western Ontario, London, Canada.
Neurosci Lett. 1988 Aug 15;91(1):1-6. doi: 10.1016/0304-3940(88)90239-x.
Experiments were done in chloralose-anesthetized cats to identify single units in the paramedian reticular nucleus (PRN) that responded to stimulation of pressor sites in the vestibular nucleus complex (VNC) and that projected directly to the intermediate gray (IG) region of the upper thoracic cord. Forty-seven units responded orthodromically to stimulation of the ipsilateral VNC with a mean latency of 6.3 +/- 0.6 ms: 44 were excited and 3 were inhibited. Of these 47 units, 29 (62%) also were antidromically activated by stimulation of the ipsilateral IG at the level of T2. These data provide electrophysiological evidence for the existence of neurons in PRN that receive VNC inputs and project directly to spinal autonomic areas, and suggest that this pathway may be involved in mediating vestibulosympathetic reflex responses associated with postural adjustments.
实验在水合氯醛麻醉的猫身上进行，以识别中旁网状核（PRN）中对前庭核复合体（VNC）中升压位点刺激有反应且直接投射到上胸段脊髓中间灰质（IG）区域的单个神经元。47个神经元对同侧VNC刺激产生顺向反应，平均潜伏期为6.3±0.6毫秒：44个被兴奋，3个被抑制。在这47个神经元中，29个（62%）也被T2水平的同侧IG刺激逆向激活。这些数据为PRN中存在接受VNC输入并直接投射到脊髓自主区域的神经元提供了电生理证据，并表明该通路可能参与介导与姿势调整相关的前庭交感反射反应。
