在细胞中表现出多酶活性和 ROS 清除能力的 Fe-N/C 单原子催化剂。
Fe-N/C single-atom catalysts exhibiting multienzyme activity and ROS scavenging ability in cells.
机构信息
Department of Chemistry, Capital Normal University, Beijing, 100048, China.
出版信息
Chem Commun (Camb). 2019 Nov 28;55(96):14534-14537. doi: 10.1039/c9cc07408b.
PMID:31740902
Abstract
Fe-N/C single atom catalysts (SACs) exhibit peroxidase-like, oxidase-like, catalase-like, and glutathione peroxidase-like activity. Fe-N/C SACs are successfully applied to control the intracellular H2O2 level. This study not only explores the types of SACs mimicking enzymes but also provides opportunities for SACs in biomedical and other bioengineering applications.
摘要
铁-氮/碳单原子催化剂（SACs）表现出过氧化物酶样、氧化酶样、过氧化氢酶样和谷胱甘肽过氧化物酶样活性。铁-氮/碳 SAC 成功应用于控制细胞内 H2O2 水平。本研究不仅探索了模拟酶的 SAC 类型，还为 SAC 在生物医学和其他生物工程应用中提供了机会。
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