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口面部疼痛——诊断与治疗挑战

OROFACIAL PAIN - DIAGNOSTIC AND THERAPEUTIC CHALLENGES.

作者信息

Badel Tomislav, Zadravec Dijana, Bašić Kes Vanja, Smoljan Mia, Kocijan Lovko Sandra, Zavoreo Iris, Krapac Ladislav, Anić Milošević Sandra

机构信息

1Department of Removable Prosthodontics, School of Dental Medicine, University of Zagreb, Zagreb, Croatia; 2Department of Diagnostic and Interventional Radiology, Sestre milosrdnice University Hospital Center, University of Zagreb, Zagreb, Croatia; 3Department of Neurology, Sestre milosrdnice University Hospital Center, University of Zagreb, Zagreb, Croatia; 4Psychiatry Hospital "Sv Ivan", Zagreb, Croatia; 5Academy of Medical Sciences of Croatia, Department of Public Health, Zagreb, Croatia; 6Department of Orthodontics, School of Dental Medicine, University of Zagreb, Zagreb, Croatia.

出版信息

Acta Clin Croat. 2019 Jun;58(Suppl 1):82-89. doi: 10.20471/acc.2019.58.s1.12.

Abstract

The concept of diagnostics and therapy of musculoskeletal and neuropathic diseases of the stomatognathic system, which are the subject of this paper, has been developing for decades. It can be said that in order to avoid misunderstanding, the orofacial pain as a clinical problem, in the narrower sense, involves non-odontogenic and non-malignant causes of orofacial region. In this study, the results of clinical diagnosis of the population of 557 consecutive patients with orofacial pain based on multidisciplinary diagnostics were evaluated. 15.6% of patients have given up on the participation in the study. It has been shown that the patients who dropped out of the study were significantly older (p=0.0411) than those who agreed to participate, but there was no difference in gender ratio (p=0.185) since the proportion of female patients prevailed. In an analysis of 84.4% of patients participating in the study, the elevated anxiety values were established (mean value on STAI 1 was 39.2 and STAI 2 was 41.1) and statistical significance was found in correlation between elevated anxiety and intensity of pain as shown on visual analogue scale on open mouth (p<0.0001). Compared to the age, the statistical significance was for STAI 1 (p=0.0097) but not for STAI 2 (p=0.5599). The most common form of therapy is Michigan stabilization splint: for disc displacement of temporomandibular joint (TMJ) in 38.9% of patients and in combination with physiotherapy in 18.7% of patients; for osteoarthritis of TMJ in 28.4% and in combination with physiotherapy in 26.4% of patients. The treatment with anticonvulsant drugs for trigeminal neuralgia predominates in 54.3% of patients, which is combined with acupuncture in 25.7% of patients and only acupuncture in 17.1% of patients. In this study, a multidisciplinary co-operation in initial diagnostics and differential was designed to develop subspecialist knowledge on orofacial pain.

摘要

作为本文主题的口颌系统肌肉骨骼和神经疾病的诊断与治疗概念已发展了数十年。可以说,为避免误解,狭义上作为临床问题的口面部疼痛涉及口面部区域的非牙源性和非恶性病因。在本研究中,基于多学科诊断对557例连续的口面部疼痛患者群体的临床诊断结果进行了评估。15.6%的患者放弃参与研究。结果显示,退出研究的患者比同意参与的患者年龄显著更大(p = 0.0411),但性别比例没有差异(p = 0.185),因为女性患者占比更高。在对参与研究的84.4%患者的分析中,确定存在焦虑值升高(状态 - 特质焦虑量表1的平均值为39.2,状态 - 特质焦虑量表2的平均值为41.1),并且发现焦虑升高与张口视觉模拟量表上显示的疼痛强度之间存在统计学相关性(p < 0.0001)。与年龄相比,状态 - 特质焦虑量表1具有统计学意义(p = 0.0097),但状态 - 特质焦虑量表2没有(p = 0.5599)。最常见的治疗形式是密歇根稳定矫治器:用于颞下颌关节(TMJ)盘移位的患者占38.9%,与物理治疗联合使用的患者占18.7%;用于TMJ骨关节炎的患者占28.4%,与物理治疗联合使用的患者占26.4%。54.3%的三叉神经痛患者以抗惊厥药物治疗为主,其中25.7%的患者联合针灸治疗,仅17.1%的患者仅接受针灸治疗。在本研究中,在初始诊断和鉴别诊断中设计了多学科合作,以发展关于口面部疼痛的亚专业知识。

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