Jayagandhi Sathishkumar, Cheruvu Saranya Chithra, Manimaran Vinoth, Mohanty Sanjeev
Department of ENT Head and Neck Surgery, Sri Ramachandra Medical College and Hospital, Porur, Chennai, 600116 India.
Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):923-926. doi: 10.1007/s12070-019-01592-3. Epub 2019 Feb 9.
Deep neck spaces are still common in developing countries like India, even though its less prevalent in developed nations. It can lead to serious complications like jugular vein thrombosis and dissemination of infection if not diagnosed early and intervened. This is a retrospective chart review of 52 patients from 2014 to 2017 in a tertiary care hospital. Only patients with infection deeper to the superficial fascia of neck were included. Submandibular space infection was the most common and precipitating factor being dental infection. Most common comorbid condition was diabetes mellitus. Klebsiella pneumoniae was the most common isolated organism and few patients had mixed culture with anaerobes. Injectable cephalosporin with metronidazole was the most effective antibiotic combination against such infections. Low threshold for early surgical intervention reduce hospital stay and enable quick recovery of patients. Usage of over the counter antibiotics masks the conditions and complicate diagnosis and treatment of this condition.
尽管在发达国家颈部深部间隙感染并不常见，但在印度等发展中国家仍很常见。如果不及早诊断和干预，它可能会导致严重的并发症，如颈静脉血栓形成和感染扩散。这是对一家三级护理医院2014年至2017年52例患者的回顾性病历审查。仅纳入颈部浅筋膜深层感染的患者。颌下间隙感染最为常见，诱发因素为牙齿感染。最常见的合并症是糖尿病。肺炎克雷伯菌是最常见的分离出的病原体，少数患者为厌氧菌混合培养。注射用头孢菌素与甲硝唑是针对此类感染最有效的抗生素组合。早期手术干预的低门槛可减少住院时间并使患者快速康复。使用非处方抗生素会掩盖病情并使该病的诊断和治疗复杂化。
