F-FDG PET/CT 在疑似眼内结节病和结核病中的作用。
The Role of F-FDG PET/CT in Suspected Intraocular Sarcoidosis and Tuberculosis.
机构信息
Divisions of Nuclear Medicine, Tygerberg Hospital and Stellenbosch University, Cape Town, South Africa.
Ophthalmology, Tygerberg Hospital and Stellenbosch University, Cape Town, South Africa.
出版信息
Ocul Immunol Inflamm. 2021 Apr 3;29(3):530-536. doi: 10.1080/09273948.2019.1685109. Epub 2019 Nov 19.
: To determine the utility of fluorine-18 fluorodeoxyglucose Positron Emission Tomography Computed Tomography (FDG PET/CT) in patients with suspected ocular sarcoidosis (OS) or intraocular tuberculosis (IOTB) in a resource-constrained, TB endemic area.: Independent review of the FDG PET/CTs, Computed Tomography (CT) scans and chest radiographs (CXRs) of patients with suspected OS or IOTB and inconclusive conventional workup.: Twenty-nine PET/CTs and CXRs were reviewed, with 38% of PET/CTs and CTs demonstrating evidence of TB or sarcoidosis, compared to 21% of CXRs. The sensitivity, specificity, positive and negative predictive values for PET/CT and CT were similar - 85.7%, 95.5%, 85.7% and 95.5% for OS, and 33.3%, 100%, 100% and 68% for IOTB respectively and for CXR, 57.1%, 100%, 100% and 88% for OS, and 16.7%, 100%, 100% and 63% for IOTB.: PET/CT added no significant additional benefit over Chest CT in patients with suspected OS or IOTB.
在资源有限且结核病流行的地区，评估氟-18 氟代脱氧葡萄糖正电子发射断层扫描计算机断层扫描（FDG PET/CT）在疑似眼结节病（OS）或眼内结核（IOTB）患者中的效用。
对疑似 OS 或 IOTB 患者的 FDG PET/CT、计算机断层扫描（CT）和胸部 X 光片（CXR）进行独立评估，且常规检查结果不确定。
共回顾了 29 例 PET/CT 和 CXR，与 CXR 的 21%相比，38%的 PET/CT 和 CT 显示有 TB 或结节病的证据。PET/CT 和 CT 的灵敏度、特异性、阳性和阴性预测值相似-OS 分别为 85.7%、95.5%、85.7%和 95.5%，IOTB 分别为 33.3%、100%、100%和 68%，CXR 分别为 57.1%、100%、100%和 88%，OS 分别为 16.7%、100%、100%和 63%。
对于疑似 OS 或 IOTB 患者，PET/CT 与胸部 CT 相比并未显著增加额外获益。
Zotero 插件