Sunohara A, Mizuno N, Sakai M, Kawabe Y, Sakakibara S
Department of Dermatology, Nagoya City University Medical School, Japan.
Photodermatol. 1988 Jun;5(3):139-45.
Action spectra for UV erythema and reproduction of the skin lesions in 4 patients with hydroa vacciniforme (HV) were studied. Vesicles were successfully reproduced by repeated daily monochromatic irradiations of 330, 340, 350 and 360 nm for 5, 6 or 7 days. The daily doses were equivalent to global solar radiation for 70-190 min. The vesicles produced were identical to those of HV, macroscopically and histologically. Repeated daily exposures to a small dose of UVA produced vesicles, whereas a large but single exposure to UVA failed to do so. Daily exposures to UVB failed to produce the vesicles. The minimal erythema dose (MED) was lower than the minimum limits of the normal persons in the 290-310 nm range.
研究了4例种痘样水疱病（HV）患者紫外线红斑的作用光谱及皮肤损害的再现情况。通过每天重复进行330、340、350和360nm的单色照射5、6或7天，成功再现了水疱。每日剂量相当于70 - 190分钟的全球太阳辐射量。所产生的水疱在宏观和组织学上与HV的水疱相同。每天重复暴露于小剂量UVA可产生水疱，而大剂量单次暴露于UVA则不能。每日暴露于UVB未能产生水疱。在290 - 310nm范围内，最小红斑量（MED）低于正常人的最低限度。
