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种痘样水疱病:紫外线A诱导的皮损

Hydroa vacciniforme: induction of lesions with ultraviolet A.

作者信息

Halasz C L, Leach E E, Walther R R, Poh-Fitzpatrick M B

出版信息

J Am Acad Dermatol. 1983 Feb;8(2):171-6. doi: 10.1016/s0190-9622(83)70019-8.

Abstract

Hydroa vacciniforme is a rare photosensitivity disorder with onset in childhood. The distinctive lesion is a vesicle which heals with scarring. We report a case of hydroa vacciniforme in which an abnormal minimal erythema dose to wavelengths of 322 to 370 nm within the ultraviolet A (UVA) range was demonstrated. Vesicles could be induced only with multiple exposures to UVA. Increased tolerance to UVA erythema was induced by multiple UVB exposures, although tanning was poor. Of note were the presence of several halo nevi and a history of the loss of ability to tan. The clinical features and appropriate laboratory evaluation of hydroa vacciniforme are reviewed.

摘要

种痘样水疱病是一种罕见的儿童期起病的光敏性疾病。其特征性损害是水疱,愈后留瘢痕。我们报告1例种痘样水疱病患者,该患者对紫外线A(UVA)范围内波长322~370nm的最小红斑量异常。只有多次暴露于UVA才能诱发水疱。尽管晒黑效果不佳,但多次中波紫外线(UVB)照射可诱导对UVA红斑的耐受性增加。值得注意的是,该患者存在多个晕痣,并有晒黑能力丧失史。本文对种痘样水疱病的临床特征及适当的实验室评估进行了综述。

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Hydroa vacciniforme: induction of lesions with ultraviolet A.种痘样水疱病:紫外线A诱导的皮损
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