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《适合上学研究方案:儿童早期生长、健康行为、营养、心脏代谢风险及儿童入学准备的发育决定因素,一项前瞻性队列研究》

Fit for School Study protocol: early child growth, health behaviours, nutrition, cardiometabolic risk and developmental determinants of a child's school readiness, a prospective cohort.

作者信息

Birken Catherine S, Omand Jessica A, Nurse Kim M, Borkhoff Cornelia M, Koroshegyi Christine, Lebovic Gerald, Maguire Jonathon L, Mamdani Muhammad, Parkin Patricia C, Randall Simpson Janis, Tremblay Mark S, Duku Eric, Reid-Westoby Caroline, Janus Magdalena

机构信息

Division of Paediatric Medicine and the Paediatric Outcomes Research Team (PORT), Hospital for Sick Children, Toronto, Ontario, Canada.

Child Health Evaluative Sciences, Hospital for Sick Children Research Institute, Toronto, Ontario, Canada.

出版信息

BMJ Open. 2019 Nov 19;9(11):e030709. doi: 10.1136/bmjopen-2019-030709.

Abstract

INTRODUCTION

School readiness is a multidimensional construct that includes cognitive, behavioural and emotional aspects of a child's development. School readiness is strongly associated with a child's future school success and well-being. The Early Development Instrument (EDI) is a reliable and valid teacher-completed tool for assessing school readiness in children at kindergarten age. A substantial knowledge gap exists in understanding how early child growth, health behaviours, nutrition, cardiometabolic risk and development impact school readiness. The primary objective was to determine if growth patterns, measured by body mass index trajectories in healthy children aged 0-5 years, are associated with school readiness at ages 4-6 years (kindergarten age). Secondary objectives were to determine if other health trajectories, including health behaviours, nutrition, cardiometabolic risk and development, are associated with school readiness at ages 4-6 years. This paper presents the Fit for School Study protocol.

METHODS AND ANALYSIS

This is an ongoing prospective cohort study. Parents of children enrolled in the The Applied Health Research Group for Kids (TARGet Kids!) practice-based research network are invited to participate in the Fit for School Study. Child growth, health behaviours, nutrition, cardiometabolic risk and development data are collected annually at health supervision visits and linked to EDI data collected by schools. The primary and secondary analyses will use a two-stage process: (1) latent class growth models will be used to first determine trajectory groups, and (2) generalised linear mixed models will be used to examine the relationship between exposures and EDI results.

ETHICS AND DISSEMINATION

The research ethics boards at The Hospital for Sick Children, Unity Health Toronto and McMaster University approved this study, and research ethics approval was obtained from each school board with a student participating in the study. The findings will be presented locally, nationally and internationally and will be published in peer-reviewed journals.

TRIAL REGISTRATION NUMBER

NCT01869530.

摘要

引言

入学准备是一个多维度的概念,涵盖儿童发展的认知、行为和情感方面。入学准备与儿童未来的学业成就和幸福感密切相关。早期发展工具(EDI)是一种可靠且有效的由教师填写的工具,用于评估幼儿园年龄段儿童的入学准备情况。在理解儿童早期生长、健康行为、营养、心脏代谢风险和发育如何影响入学准备方面,存在相当大的知识空白。主要目标是确定以0至5岁健康儿童的体重指数轨迹衡量的生长模式是否与4至6岁(幼儿园年龄)的入学准备相关。次要目标是确定其他健康轨迹,包括健康行为、营养、心脏代谢风险和发育,是否与4至6岁的入学准备相关。本文介绍了“适合上学”研究方案。

方法与分析

这是一项正在进行的前瞻性队列研究。邀请参与基于实践的研究网络“儿童应用健康研究小组”(TARGet Kids!)的儿童家长参加“适合上学”研究。在健康监督访视时每年收集儿童生长、健康行为、营养、心脏代谢风险和发育数据,并与学校收集的EDI数据相关联。主要和次要分析将采用两阶段过程:(1)潜在类别生长模型将首先用于确定轨迹组,(2)广义线性混合模型将用于检验暴露与EDI结果之间的关系。

伦理与传播

病童医院、多伦多团结健康中心和麦克马斯特大学的研究伦理委员会批准了本研究,并获得了每所参与学生研究的学校董事会的研究伦理批准。研究结果将在本地、全国和国际范围内展示,并将发表在同行评审期刊上。

试验注册号

NCT01869530。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0313/6886995/08b18b4391fa/bmjopen-2019-030709f01.jpg

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