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先天性动静脉畸形:个体化栓塞治疗

Congenital arteriovenous malformations: tailored embolotherapy.

作者信息

Widlus D M, Murray R R, White R I, Osterman F A, Schreiber E R, Satre R W, Mitchell S E, Kaufman S L, Williams G M, Weiland A J

机构信息

Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins Medical Institutions, Baltimore, MD 21205-2191.

出版信息

Radiology. 1988 Nov;169(2):511-6. doi: 10.1148/radiology.169.2.3175000.

Abstract

Congenital arteriovenous malformations (AVMs) involving the pelvis or an extremity were occluded in 16 symptomatic patients, who subsequently underwent tailored embolotherapy. An additional 11 patients did not undergo embolization due to unfavorable vascular anatomy or lack of significant symptoms. Permanent occlusive agents including isobutyl cyanoacrylate, particles of polyvinyl alcohol foam, and coils were used to embolize the multiple feeding vessels and, when possible, the nidus of the AVM. All patients experienced dramatic reduction in pain and resolution of ulceration and bleeding, with a mean follow-up period of 41 months. Symptoms recurred in four patients but again resolved with repeat embolization. The authors conclude that selective and repetitive embolization is highly effective in palliation of symptomatic congenital AVMs.

摘要

16例有症状的先天性骨盆或肢体动静脉畸形(AVM)患者接受了闭塞治疗,随后接受了定制的栓塞治疗。另外11例患者因血管解剖结构不佳或缺乏明显症状而未接受栓塞治疗。使用包括异丁基氰基丙烯酸酯、聚乙烯醇泡沫颗粒和弹簧圈在内的永久性闭塞剂栓塞多条供血血管,并在可能的情况下栓塞AVM的病灶。所有患者疼痛均显著减轻,溃疡和出血症状消失,平均随访期为41个月。4例患者症状复发,但再次栓塞后症状又得到缓解。作者得出结论,选择性和重复性栓塞在缓解有症状的先天性AVM方面非常有效。

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