IEEE Trans Med Imaging. 2020 May;39(5):1615-1625. doi: 10.1109/TMI.2019.2953717. Epub 2019 Nov 15.
Surgical smoke removal algorithms can improve the quality of intra-operative imaging and reduce hazards in image-guided surgery, a highly desirable post-process for many clinical applications. These algorithms also enable effective computer vision tasks for future robotic surgery. In this article, we present a new unsupervised learning framework for high-quality pixel-wise smoke detection and removal. One of the well recognized grand challenges in using convolutional neural networks (CNNs) for medical image processing is to obtain intra-operative medical imaging datasets for network training and validation, but availability and quality of these datasets are scarce. Our novel training framework does not require ground-truth image pairs. Instead, it learns purely from computer-generated simulation images. This approach opens up new avenues and bridges a substantial gap between conventional non-learning based methods and which requiring prior knowledge gained from extensive training datasets. Inspired by the Generative Adversarial Network (GAN), we have developed a novel generative-collaborative learning scheme that decomposes the de-smoke process into two separate tasks: smoke detection and smoke removal. The detection network is used as prior knowledge, and also as a loss function to maximize its support for training of the smoke removal network. Quantitative and qualitative studies show that the proposed training framework outperforms the state-of-the-art de-smoking approaches including the latest GAN framework (such as PIX2PIX). Although trained on synthetic images, experimental results on clinical images have proved the effectiveness of the proposed network for detecting and removing surgical smoke on both simulated and real-world laparoscopic images.
手术烟雾去除算法可以提高术中成像质量,降低影像引导手术中的危害,这是许多临床应用所期望的后处理过程。这些算法还为未来的机器人手术提供了有效的计算机视觉任务。在本文中,我们提出了一种新的用于高质量像素级烟雾检测和去除的无监督学习框架。在使用卷积神经网络(CNN)进行医学图像处理时,一个众所周知的重大挑战是获得用于网络训练和验证的术中医学成像数据集,但这些数据集的可用性和质量都很稀缺。我们的新型训练框架不需要真实图像对。相反,它纯粹从计算机生成的模拟图像中学习。这种方法开辟了新的途径,在传统的非学习方法和需要从大量训练数据集中获得先验知识的方法之间架起了一座桥梁。受生成对抗网络(GAN)的启发,我们开发了一种新的生成协作学习方案,将去烟过程分解为两个独立的任务:烟雾检测和烟雾去除。检测网络被用作先验知识,也用作损失函数,以最大限度地支持对烟雾去除网络的训练。定量和定性研究表明,所提出的训练框架优于最先进的去烟方法,包括最新的 GAN 框架(如 PIX2PIX)。尽管是在合成图像上进行训练,但对临床图像的实验结果证明了所提出的网络在模拟和真实腹腔镜图像上检测和去除手术烟雾的有效性。