新生儿睡眠呼吸紊乱及其对长期影响的意义。

Sleep disordered breathing (SDB) in neonates and implications for its long-term impact.

机构信息

Department of Neonatology, The Children's Hospital at Westmead, Sydney, NSW, Australia; Discipline of Paediatrics & Child Health, Sydney Medical School, University of Sydney, Australia.

Department of Respiratory Medicine, The Children's Hospital at Westmead, Sydney, NSW, Australia; Discipline of Paediatrics & Child Health, Sydney Medical School, University of Sydney, Australia.

出版信息

Paediatr Respir Rev. 2020 Apr;34:3-8. doi: 10.1016/j.prrv.2019.10.003. Epub 2019 Oct 30.

DOI:10.1016/j.prrv.2019.10.003

PMID:31753754

Abstract

Sleep-disordered breathing (SDB) is a significant cause of morbidity in neonates and young infants. SDB occurs more commonly in preterm infants and in neonates with underlying syndromes. Recent evidence shows that infants with obstructive sleep apnoea (OSA) or SDB have greater health care resource utilization, including longer hospital stay. Management of SDB includes non-invasive ventilation or surgical interventions tailored to the patient. Screening high risk newborns should allow for early diagnosis and timely therapeutic intervention for this population. However, the thresholds for diagnosing SDB and for guiding and implementing treatment in neonates remain unclear. A collective effort is required to standardize the practice worldwide. This article will discuss neonatal sleep physiology and characteristics of neonatal sleep, with an emphasis on the epidemiology and diagnosis of SDB in neonates and its implications for long term outcomes.

摘要

睡眠障碍性呼吸（SDB）是新生儿和婴幼儿发病率的重要原因。SDB 更常见于早产儿和有潜在综合征的新生儿。最近的证据表明，患有阻塞性睡眠呼吸暂停（OSA）或 SDB 的婴儿会更多地利用医疗保健资源，包括住院时间更长。SDB 的治疗包括针对患者的无创通气或手术干预。对高危新生儿进行筛查可以使该人群尽早诊断并及时进行治疗。然而，诊断 SDB 的标准以及指导和实施新生儿治疗的标准仍不清楚。需要共同努力使全球的实践标准化。本文将讨论新生儿睡眠生理学和新生儿睡眠特征，重点介绍新生儿 SDB 的流行病学和诊断及其对长期结局的影响。