Faculty of Veterinary Medicine, University of Teramo, Teramo, Italy
Faculty of Veterinary Medicine, University of Teramo, Teramo, Italy.
Vet Rec. 2020 Sep 5;187(5):e34. doi: 10.1136/vr.105528. Epub 2019 Nov 21.
is the most important nematode affecting the respiratory tract of cats in terms of prevalence and clinical relevance. The aim of this randomised controlled field study was to confirm the efficacy of the spot-on containing emodepside/praziquantel (Profender, Bayer Animal Health) in the treatment of aelurostrongylosis.
Seventeen cats with aelurostrongylosis and presenting with clinical and/or radiographic signs were included in the study. Eight cats received two biweekly doses of emodepside/praziquantel, while nine cats were allocated to a control group and received a rescue treatment at the end of the study. Clinical response was the primary outcome, while the secondary end point was the reduction of larval shedding in faeces.
Two weeks after the first application, the cats showed a significant, though partial, recovery of clinical signs with complete clinical and parasitological resolution. The resolution of inflammatory leucogram and a significant reduction of radiographic lesions were observed two weeks after the second treatment. Red blood cells and albumin values significantly increased after eight weeks from the second application, together with the complete regression of radiographic patterns.
Two applications of this spot-on solution two weeks apart assured complete cessation of larval shedding and led to a complete clinical, clinicopathological and radiographic recovery.
是猫呼吸道最重要的寄生线虫，在流行率和临床相关性方面都是如此。本随机对照现场研究的目的是确认含有埃莫德昔/吡喹酮（拜耳动保）的滴剂在治疗犬弓首蛔虫病方面的疗效。
17 只患有犬弓首蛔虫病且出现临床和/或放射影像学迹象的猫被纳入本研究。8 只猫接受了两次两周一次的埃莫德昔/吡喹酮剂量，而 9 只猫被分配到对照组，并在研究结束时接受了救援治疗。临床反应是主要终点，而次要终点是粪便中幼虫脱落的减少。
首次应用后两周，猫的临床症状有显著但部分恢复，临床和寄生虫学完全缓解。第二次治疗两周后，炎症性白细胞计数得到解决，放射影像学病变显著减少。从第二次应用后 8 周开始，红细胞和白蛋白值显著增加，放射影像学模式完全消退。
这种滴剂每两周使用一次，共两次，可确保幼虫完全停止脱落，并导致完全的临床、临床病理和放射影像学恢复。
