Phillips Bob
Centre for Reviews and Dissemination, University of York, York, Yorkshire, YO10 5DD, UK.
Leeds Children's Hospital, Leeds General Infirmary, Leeds, Yorkshire, LS1 9EX, UK.
F1000Res. 2019 Nov 12;8. doi: 10.12688/f1000research.19337.1. eCollection 2019.
A major consequence of the intensive multi-modal chemotherapy commonly used to treat malignancies in childhood is life-threatening infection, frequently during periods of profound neutropenia. Recent advances have been made in all areas of management, from trying to prevent infection to getting patients off antimicrobials and home again in the shortest, safest way. Potential avenues of further research are outlined for readers to be aware of in the next few years.
常用于治疗儿童恶性肿瘤的强化多模式化疗的一个主要后果是危及生命的感染,这种感染经常发生在严重中性粒细胞减少的时期。从试图预防感染到以最短、最安全的方式让患者停用抗菌药物并再次回家,管理的各个方面都取得了最新进展。本文概述了未来几年可供读者了解的进一步研究的潜在途径。