Baylor College of Medicine, McNair Campus, 7200 Cambridge St., Suite 8B, Houston, TX, 77030, USA.
Baylor College of Medicine, 6620 Main St., Houston, TX, 77030, USA.
Curr Atheroscler Rep. 2019 Nov 21;21(12):53. doi: 10.1007/s11883-019-0812-8.
In this review, we describe the mechanism behind coronary artery calcification formation and detection, as well as its implication in cardiovascular disease (CVD) risk stratification, intervention, and prognosis in asymptomatic individuals.
Multiple cohort and population studies have shown that coronary artery calcium scoring is effective and reproducible in predicting the risk for cardiovascular disease. The updated 2018 ACC/AHA guideline has incorporated consideration of coronary artery calcification testing into cardiovascular disease risk stratification and therapy guidance. Coronary artery calcification's evidence-based role in detection, risk stratification, and ultimately its unique influence on therapeutic intervention and prognosis of cardiovascular disease in asymptomatic population is increasingly being recognized..
在本次综述中,我们描述了冠状动脉钙化形成和检测的机制,以及其在无症状个体的心血管疾病(CVD)风险分层、干预和预后中的意义。
多项队列和人群研究表明,冠状动脉钙化积分在预测心血管疾病风险方面是有效且可重复的。2018 年 ACC/AHA 指南更新版已将冠状动脉钙化检测纳入心血管疾病风险分层和治疗指导。冠状动脉钙化在无症状人群中的检测、风险分层,以及最终对治疗干预和预后的独特影响,其循证作用正日益得到认可。