Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Indian J Ophthalmol. 2019 Dec;67(12):2013-2018. doi: 10.4103/ijo.IJO_533_19.
To describe the swept-source optical coherence tomography (SS-OCT) features of regressed macular retinoblastoma (RB).
A cross-sectional observational study was carried out in 13 patients with regressed macular RB with good fixation in at least one eye. Fundus photography and SS-OCT were documented. High-resolution scans with good signal strength were selected. The types of clinical regression and SS-OCT characteristics of the regressed lesions (presence of vitreous detachment, intratumor schisis/cavitation, calcification, foveal dip, and OCT pattern) were noted.
Of the 13 eyes, 7 (53%) were group B, 4 (30%) were group C, and 2 (17%) were group D. Lesion involving fovea was seen in seven eyes (53%). On SS-OCT, the lesion was isodense to hyperdense in all cases. Three patterns of regressed RB were noted on OCT. Intralesion calcification was noted in eight cases. Subretinal fluid was not detected in any of the cases.
SS-OCT is a useful technology to image and analyze cases of regressed macular RB including large lesions. SS-OCT system helps in successful imaging even in smaller children.
描述消退型黄斑部视网膜母细胞瘤（RB）的扫频源光相干断层扫描（SS-OCT）特征。
对至少有一只眼固视良好的 13 例消退型黄斑部 RB 患者进行了一项横断面观察性研究。记录眼底照相和 SS-OCT 检查。选择具有良好信号强度的高分辨率扫描。注意临床消退的类型和消退病变的 SS-OCT 特征（是否存在玻璃体脱离、肿瘤内分裂/空洞、钙化、中心凹下凹和 OCT 模式）。
13 只眼中，7 只（53%）为 B 组，4 只（30%）为 C 组，2 只（17%）为 D 组。7 只眼（53%）累及黄斑。SS-OCT 显示所有病例的病变均为等密度至高密度。OCT 上观察到 3 种消退型 RB 模式。8 例发现肿瘤内钙化。所有病例均未检测到视网膜下液。
SS-OCT 是一种有用的成像和分析包括大病变在内的消退型黄斑部 RB 的技术。SS-OCT 系统有助于即使是较小的儿童也能成功成像。
