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专家组关于皮肤科手术阿片类药物处方指南的共识。

An expert panel consensus on opioid-prescribing guidelines for dermatologic procedures.

机构信息

Department of Dermatology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.

Department of Dermatology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.

出版信息

J Am Acad Dermatol. 2020 Mar;82(3):700-708. doi: 10.1016/j.jaad.2019.09.080. Epub 2019 Nov 12.

DOI:10.1016/j.jaad.2019.09.080
PMID:31756403
Abstract

BACKGROUND

Opioid overprescribing is a major contributor to the opioid crisis. The lack of procedure-specific guidelines contributes to the vast differences in prescribing practices.

OBJECTIVE

To create opioid-prescribing consensus guidelines for common dermatologic procedures.

METHODS

We used a 4-step modified Delphi method to conduct a systematic discussion among a panel of dermatologists in the fields of general dermatology, dermatologic surgery, and cosmetics/phlebology to develop opioid prescribing guidelines for some of the most common dermatologic procedural scenarios. Guidelines were developed for opioid-naive patients undergoing routine procedures. Opioid tablets were defined as oxycodone 5-mg oral equivalents.

RESULTS

Postoperative pain after most uncomplicated procedures (76%) can be adequately managed with acetaminophen and/or ibuprofen. Group consensus identified no specific dermatologic scenario that routinely requires more than 15 oxycodone 5-mg oral equivalents to manage postoperative pain. Group consensus found that 23% of the procedural scenarios routinely require 1 to 10 opioid tablets, and only 1 routinely requires 1 to 15 opioid tablets.

LIMITATIONS

These recommendations are based on expert consensus in lieu of quality evidence-based outcomes research. These recommendations must be individualized to accommodate patients' comorbidities.

CONCLUSIONS

Procedure-specific opioid prescribing guidelines may serve as a foundation to produce effective and responsible postoperative pain management strategies after dermatologic interventions.

摘要

背景

阿片类药物的过度开方是阿片类药物危机的主要原因之一。缺乏针对具体操作的指南导致了处方实践的巨大差异。

目的

为常见皮肤科操作创建阿片类药物开方共识指南。

方法

我们使用了一个 4 步改良德尔菲法,在普通皮肤科、皮肤科手术和美容/静脉学领域的皮肤科医生小组中进行了系统讨论,为一些最常见的皮肤科操作场景制定了阿片类药物开方指南。这些指南适用于接受常规操作的阿片类药物初治患者。阿片类药物片剂定义为 5 毫克羟考酮口服等效物。

结果

大多数非复杂性操作(76%)后的术后疼痛可以通过对乙酰氨基酚和/或布洛芬充分管理。专家组一致认为,没有特定的皮肤科场景常规需要超过 15 片羟考酮 5 毫克口服等效物来管理术后疼痛。专家组认为,23%的操作场景常规需要 1 到 10 片阿片类药物片剂,只有 1 个场景常规需要 1 到 15 片阿片类药物片剂。

局限性

这些建议是基于专家共识,而非基于高质量的循证结果研究。这些建议必须个体化以适应患者的合并症。

结论

特定操作的阿片类药物开方指南可以作为制定有效的和负责任的皮肤科干预后术后疼痛管理策略的基础。

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