Suppr超能文献

常见手术操作的阿片类药物处方指南:专家小组共识。

Opioid-Prescribing Guidelines for Common Surgical Procedures: An Expert Panel Consensus.

机构信息

Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.

Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.

出版信息

J Am Coll Surg. 2018 Oct;227(4):411-418. doi: 10.1016/j.jamcollsurg.2018.07.659. Epub 2018 Aug 14.

Abstract

BACKGROUND

One in 16 surgical patients prescribed opioids becomes a long-term user. Overprescribing opioids after surgery is common, and the lack of multidisciplinary procedure-specific guidelines contributes to the wide variation in opioid prescribing practices. We hypothesized that a single-institution, multidisciplinary expert panel can establish consensus on ideal opioid prescribing for select common surgical procedures.

STUDY DESIGN

We used a 3-step modified Delphi method involving a multidisciplinary expert panel of 6 relevant stakeholder groups (surgeons, pain specialists, outpatient surgical nurse practitioners, surgical residents, patients, and pharmacists) to develop consensus ranges for outpatient opioid prescribing at the time of discharge after 20 common procedures in 8 surgical specialties. Prescribing guidelines were developed for opioid-naïve adult patients without chronic pain undergoing uncomplicated procedures. The number of opioid tablets was defined using oxycodone 5 mg oral equivalents.

RESULTS

For all 20 surgical procedures reviewed, the minimum number of opioid tablets recommended by the panel was 0. Ibuprofen was recommended for all patients unless medically contraindicated. The maximum number of opioid tablets varied by procedure (median 12.5 tablets), with panel recommendations of 0 opioid tablets for 3 of 20 (15%) procedures, 1 to 15 opioid tablets for 11 of 20 (55%) procedures, and 16 to 20 tablets for 6 of 20 (30%) procedures. Overall, patients who had the procedures voted for lower opioid amounts than surgeons who performed them.

CONCLUSIONS

Procedure-specific prescribing recommendations may help provide guidance to clinicians who are currently overprescribing opioids after surgery. Multidisciplinary, patient-centered consensus guidelines for more procedures are feasible and may serve as a tool in combating the opioid crisis.

摘要

背景

接受阿片类药物处方的患者中有 16 分之一成为长期使用者。手术后过度开具阿片类药物的情况很常见,缺乏多学科特定程序指南导致阿片类药物处方实践存在广泛差异。我们假设,一个单一机构的多学科专家小组可以就选定常见手术的理想阿片类药物处方达成共识。

研究设计

我们使用了三步法修改后的 Delphi 方法,涉及 6 个相关利益相关者群体(外科医生、疼痛专家、门诊外科护士从业者、外科住院医师、患者和药剂师)的多学科专家小组,以确定 8 个外科专业的 20 种常见手术中出院时门诊阿片类药物处方的共识范围。为没有慢性疼痛且接受简单手术的阿片类药物初治成年患者制定了处方指南。使用羟考酮 5 毫克口服等效物定义了阿片类药物片剂的数量。

结果

对于所有 20 种手术程序,专家组推荐的最低阿片类药物片剂数量为 0。除非医学上禁忌,否则建议所有患者使用布洛芬。阿片类药物片剂的最大数量因程序而异(中位数为 12.5 片),专家组建议的 20 项手术中的 3 项(15%)无阿片类药物片剂,11 项(55%)为 1 至 15 片阿片类药物片剂,6 项(30%)为 16 至 20 片阿片类药物片剂。总体而言,接受手术的患者比进行手术的外科医生投票赞成的阿片类药物数量更少。

结论

特定程序的处方建议可能有助于为目前手术后过度开具阿片类药物的临床医生提供指导。针对更多程序的多学科、以患者为中心的共识指南是可行的,并可能成为应对阿片类药物危机的工具。

相似文献

10
Opioid Prescribing Patterns After Anorectal Surgery.肛肠手术后阿片类药物的处方模式。
J Surg Res. 2020 Nov;255:632-640. doi: 10.1016/j.jss.2020.05.098. Epub 2020 Jul 11.

引用本文的文献

2
Persistent Opioid Use Following Major Orthopedic Surgery.骨科大手术后持续使用阿片类药物。
Curr Pain Headache Rep. 2025 May 29;29(1):92. doi: 10.1007/s11916-025-01404-0.

本文引用的文献

10
A 1980 Letter on the Risk of Opioid Addiction.一封关于阿片类药物成瘾风险的1980年信件。
N Engl J Med. 2017 Jun 1;376(22):2194-2195. doi: 10.1056/NEJMc1700150.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验