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较低的去脂体重是否介导了亚洲老年人跌倒与较高体重指数之间的关系?

Does Lower Lean Body Mass Mediate the Relationship Between Falls and Higher Body Mass Index in Asian Older Persons?

作者信息

Kioh Sheng H, Mat Sumaiyah, Kamaruzzaman Shahrul B, Ibrahim Fatimah, Mokhtar Mas S, Hairi Noran N, Cumming Robert G, Myint Phyo K, Tan Maw P

出版信息

J Aging Phys Act. 2019 Nov 21;28(3):426-433. doi: 10.1123/japa.2019-0011. Print 2020 Jun 1.

DOI:10.1123/japa.2019-0011
PMID:31756717
Abstract

The current evidence on the relationship between a higher body mass index (BMI) and falls in older adults is conflicting. This study, therefore, evaluated the relationship between BMI and falls and explored underlying mechanisms for this relationship. Data from 1,340 individuals from the Malaysian Elders Longitudinal Research study, obtained through home-based computer-assisted interviews and followed by hospital-based health checks, were utilized. A history of the presence of falls in the previous 12 months was obtained. The presence of at least one fall in the past 12 months was associated with a higher BMI (odds ratio = 1.03, 95% confidence interval [1.01, 1.06]). The relationship between a higher BMI and falls was, however, attenuated by a lower percentage of lean body mass, which accounted for 69% of the total effect of BMI on the risk of falls. Future studies should now investigate this aforementioned relationship prospectively.

摘要

目前关于较高体重指数(BMI)与老年人跌倒之间关系的证据相互矛盾。因此,本研究评估了BMI与跌倒之间的关系,并探讨了这种关系的潜在机制。我们使用了马来西亚老年人纵向研究中1340名个体的数据,这些数据通过家庭电脑辅助访谈获得,随后进行了基于医院的健康检查。我们获取了过去12个月内跌倒史。过去12个月内至少发生一次跌倒与较高的BMI相关(优势比 = 1.03,95%置信区间[1.01, 1.06])。然而,较高的BMI与跌倒之间的关系因较低的瘦体重百分比而减弱,瘦体重占BMI对跌倒风险总效应的69%。未来的研究现在应该前瞻性地调查上述关系。

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引用本文的文献

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BMJ Open. 2024 Nov 7;14(11):e087358. doi: 10.1136/bmjopen-2024-087358.
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Risk of falls in 4 years of follow-up among Chinese adults with diabetes: findings from the China Health and Retirement Longitudinal Study.中国成年人糖尿病患者 4 年随访期间的跌倒风险:来自中国健康与养老追踪调查的研究结果。
BMJ Open. 2021 Jun 8;11(6):e043349. doi: 10.1136/bmjopen-2020-043349.
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Impact of Knee Pain on Fear of Falling, Changes in Instrumental Activities of Daily Living, and Falls Among Malaysians Age 55 Years and Above.
膝关节疼痛对55岁及以上马来西亚人跌倒恐惧、日常生活工具性活动变化及跌倒情况的影响。
Front Public Health. 2020 Oct 14;8:571196. doi: 10.3389/fpubh.2020.571196. eCollection 2020.