European Centre for Disease Prevention and Control (ECDC), Gustav III:s Boulevard 40, 169 73 Solna, Sweden.
Toxins (Basel). 2019 Nov 20;11(12):681. doi: 10.3390/toxins11120681.
The deliberate release of biological agents with terrorist or criminal intent continues to pose concerns in the current geopolitical situation. Therefore, attention is still needed to ensure preparedness against the potential use of pathogens as unconventional weapons. Botulinum neurotoxin (BoNT) is one such biological threat, characterized by an extremely low lethal dose, high morbidity and mortality when appropriately disseminated, and the capacity to cause panic and social disruption. This paper addresses the risks of a potential release of the botulinum neurotoxin and summarizes the relevant aspects of the threat.
具有恐怖或犯罪意图的生物制剂的蓄意释放，在当前的地缘政治形势下仍令人担忧。因此，仍需关注防止将病原体作为非常规武器使用的可能性。肉毒神经毒素（BoNT）就是这样一种生物威胁，其特点是致死剂量极低，在适当传播时发病率和死亡率极高，并具有引起恐慌和社会混乱的能力。本文讨论了肉毒神经毒素潜在释放的风险，并总结了该威胁的相关方面。
