Phaff Yeast Culture Collection, Food Science and Technology, University of California Davis, Davis, CA, USA.
Department of Plant Pathology, Fungal Genetics Stock Center, Kansas State University, Manhattan, KS, USA.
J Appl Microbiol. 2020 Aug;129(2):162-174. doi: 10.1111/jam.14525. Epub 2019 Dec 12.
Collections of micro-organisms are a crucial element of life science research infrastructure but are vulnerable to loss and damage caused by natural or man-made disasters, the untimely death or retirement of personnel, or the loss of research funding. Preservation of biological collections has risen in priority due to a new appreciation for discoveries linked to preserved specimens, emerging hurdles to international collecting and decreased funding for new collecting. While many historic collections have been lost, several have been preserved, some with dramatic rescue stories. Rescued microbes have been used for discoveries in areas of health, biotechnology and basic life science. Suggestions for long-term planning for microbial stocks are listed, as well as inducements for long-term preservation.
微生物收集是生命科学研究基础设施的关键要素,但容易受到自然或人为灾害、人员意外死亡或退休、或研究资金损失的影响而丢失和损坏。由于对与保存标本相关的发现有了新的认识、国际收集面临新的障碍以及新收集的资金减少,生物收集的保存优先级有所提高。虽然许多历史收藏已经丢失,但也有一些得到了保存,其中一些具有戏剧性的抢救故事。被抢救的微生物已被用于健康、生物技术和基础生命科学等领域的发现。本文列出了微生物库存的长期规划建议,以及长期保存的诱因。