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Is SPINK1 gene mutation associated with development of pancreatic cancer? New insight from a large retrospective study.

作者信息

Suzuki Mitsuyoshi, Shimizu Toshiaki

机构信息

Department of Pediatrics, Juntendo University Faculty of Medicine, 2-1-1 Hongo, Bunkyo-ku, 113 8421 Tokyo, Japan.

Department of Pediatrics, Juntendo University Faculty of Medicine, 2-1-1 Hongo, Bunkyo-ku, 113 8421 Tokyo, Japan.

出版信息

EBioMedicine. 2019 Dec;50:5-6. doi: 10.1016/j.ebiom.2019.10.065. Epub 2019 Nov 20.

Abstract
摘要

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本文引用的文献

1
Natural history of SPINK1 germline mutation related-pancreatitis.
EBioMedicine. 2019 Oct;48:581-591. doi: 10.1016/j.ebiom.2019.09.032. Epub 2019 Oct 15.
2
Meta-analysis of the impact of the SPINK1 c.194 + 2T > C variant in chronic pancreatitis.
Dig Liver Dis. 2020 Feb;52(2):143-148. doi: 10.1016/j.dld.2019.07.004. Epub 2019 Aug 7.
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Heterozygous Spink1 c.194+2T>C mutant mice spontaneously develop chronic pancreatitis.
Gut. 2020 May;69(5):967-968. doi: 10.1136/gutjnl-2019-318790. Epub 2019 May 29.
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Pancreatitis-Associated Genes and Pancreatic Cancer Risk: A Systematic Review and Meta-analysis.
Pancreas. 2018 Oct;47(9):1078-1086. doi: 10.1097/MPA.0000000000001145.
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Nationwide survey of hereditary pancreatitis in Japan.
J Gastroenterol. 2018 Jan;53(1):152-160. doi: 10.1007/s00535-017-1388-0. Epub 2017 Aug 31.
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Meta-analysis of the impact of SPINK1 p.N34S gene variation in Caucasic patients with chronic pancreatitis. An update.
Dig Liver Dis. 2017 Aug;49(8):847-853. doi: 10.1016/j.dld.2017.04.023. Epub 2017 May 6.
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Genetic Risk in Chronic Pancreatitis: The Trypsin-Dependent Pathway.
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Surgery for chronic pancreatitis decreases the risk for pancreatic cancer: a multicenter retrospective analysis.
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