CHU de la Guadeloupe, Univ Antilles, Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, Pointe-à-Pitre, France.
Department of Gynecology and Obstetrics, Parent and Child Division, University Hospital of Pointe-à-Pitre/Abymes, Guadeloupe, France.
J Gynecol Obstet Hum Reprod. 2020 Feb;49(2):101654. doi: 10.1016/j.jogoh.2019.101654. Epub 2019 Nov 21.
Uterine leiomyoma has been reported to be a worse problematic disease for African American than Caucasian women in the US. Data are almost non-existent for other populations of African ancestry. Our aim was to investigate the hypothesis of an equivalent influence of ethnicity on uterine leiomyomas for women of a French African-Caribbean population.
Retrospective analysis of hysterectomies performed from 2010 to 2015 at the teaching hospital of Guadeloupe (French West Indies), where most inhabitants are of West African origin, was carried out. Data of the 899 hysterectomies, including those for malignancy, were collected, in particular, uterine weight.
The indications were leiomyoma in 66.5 % of cases and leiomyomas were found in 91 % of all cases. The mean age and uterine weight were 51.7 years and 464 g for the entire population, 50.2 years and 488 g for the population without malignancies, and 47.0 years and 567 g for the population with leiomyomas.
The data were compared to those reported in the literature for several populations, notably African Americans and Caucasians in the US and mainland France. This comparison supports the hypothesis that Guadeloupean women, an African-Caribbean population, have characteristics in terms of uterine leiomyoma that are close to those of African Americans. Although confirmation is required, these results highlight the need for specific research, therapeutic approaches, and improved early management of these populations.
在美国，与白种女性相比，子宫肌瘤被报道为非裔美国女性更严重的问题性疾病。对于其他非裔人群的数据几乎不存在。我们的目的是调查非裔加勒比人群中，种族对子宫肌瘤的影响是否同样存在的假设。
对 2010 年至 2015 年在瓜德罗普岛（法属西印度群岛）教学医院进行的子宫切除术进行回顾性分析，该医院的大多数居民都来自西非。收集了 899 例子宫切除术的数据，包括恶性肿瘤，特别是子宫重量。
适应证为子宫肌瘤的占 66.5%，所有病例中发现子宫肌瘤的占 91%。整个人群的平均年龄和子宫重量分别为 51.7 岁和 464 克，无恶性肿瘤人群的平均年龄和子宫重量分别为 50.2 岁和 488 克，有子宫肌瘤人群的平均年龄和子宫重量分别为 47.0 岁和 567 克。
将这些数据与美国和法国大陆的非裔美国人、白种人等几个人群的文献报告数据进行了比较。这种比较支持了这样一种假设，即瓜德罗普岛的非裔加勒比人群在子宫肌瘤方面具有与非裔美国人相似的特征。尽管需要进一步证实，但这些结果强调了需要对这些人群进行特定的研究、治疗方法和早期管理的改进。
