Department of Surgery, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Department of Surgery, Kamuzu Central Hospital, Lilongwe, Malawi.
Injury. 2020 Jan;51(1):97-102. doi: 10.1016/j.injury.2019.11.006. Epub 2019 Nov 9.
Globally, traumatic injury is a leading cause of morbidity and mortality in low-income countries. However, trauma centers in these environments have limited resources to manage complex trauma with minimal staffing and diagnostic tools. These limitations may be exacerbated at night. We hypothesized that there is an increase in trauma-associated mortality for patients presenting during nighttime hours.
We conducted a retrospective analysis of all patients recorded in the Kamuzu Central Hospital trauma registry in Lilongwe, Malawi from January 2012 through December 2016. Nighttime was defined as 18:00 until 5:59. Patients brought in dead were excluded. A modified Poisson regression model was used to calculate the relationship between presentation at night and mortality, adjusted for significant confounders.
74,500 patients were included. During the day, crude mortality was 0.8% compared to 1.4% at night (p < 0.001). The risk ratio of mortality following night time presentation compared to day was 1.90 (95% CI 1.48, 2.42) when adjusted for injury severity, assessed by the Malawi Trauma Score (MTS), and transfer status. When stratified by the year of traumatic injury, the risk ratio of death decreased each year from 2012-2014 but increased in 2015. There was no difference in 2016.
We report the first description of diurnal variation in trauma-associated mortality in sub-Saharan Africa. Injured patients who presented at night had nearly twice the adjusted risk ratio of death compared to patients that presented during the daytime although there were yearly differences. Diurnal variation in trauma-associated mortality is a simple but important indicator of the maturity of a trauma system and should be tracked for health care system improvement.
在全球范围内,创伤是低收入国家发病率和死亡率的主要原因。然而,这些环境中的创伤中心资源有限,人员配备和诊断工具最少,难以处理复杂的创伤。这些限制在夜间可能会加剧。我们假设夜间就诊的创伤患者的死亡率会增加。
我们对 2012 年 1 月至 2016 年 12 月期间在马拉维利隆圭的卡姆祖中央医院创伤登记处记录的所有患者进行了回顾性分析。夜间定义为 18:00 至 5:59。排除送来时已经死亡的患者。使用修正泊松回归模型计算夜间就诊与死亡率之间的关系,调整了显著混杂因素。
共纳入 74500 例患者。白天的粗死亡率为 0.8%,而夜间为 1.4%(p<0.001)。与白天就诊相比,夜间就诊的死亡率风险比为 1.90(95%CI 1.48,2.42),调整了损伤严重程度(由马拉维创伤评分(MTS)评估)和转院情况。按创伤发生年份分层时,2012-2014 年每年死亡风险比降低,但 2015 年增加。2016 年没有差异。
我们首次描述了撒哈拉以南非洲创伤相关死亡率的日变化。与白天就诊的患者相比,夜间就诊的受伤患者的死亡调整风险比几乎增加了一倍,尽管每年有所不同。创伤相关死亡率的日变化是创伤系统成熟度的一个简单但重要的指标,应进行跟踪以改善医疗保健系统。