肠炎沙门氏菌和鼠伤寒沙门氏菌在体外实验中形成的微生物联合体中的相互作用。

Interaction of Salmonella enteritidis and Salmonella typhimurium in Microbial Association Formed by Them in In Vitro Experiment.

作者信息

Rakov A V, Yakovlev A A, Kuznetsova N A

机构信息

G. P. Somov Research Institute of Epidemiology and Microbiology, Vladivostok, Russia.

出版信息

Bull Exp Biol Med. 2019 Nov;168(1):69-71. doi: 10.1007/s10517-019-04649-z. Epub 2019 Nov 25.

DOI:10.1007/s10517-019-04649-z

PMID:31761982

Abstract

We studied the interaction of Salmonella enteritidis and Salmonella typhimurium in the microbial association formed by these microorganisms in vitro. It was found that S. typhimurium in microbial association in LB-broth inhibited reproduction of S. enteritidis, which attested to its higher competitiveness. The concentration of S. typhimurium in the medium in 6 h reached 92-93% of the total number of bacteria. Parallel growth of the populations of S. enteritidis and S. typhimurium was observed only during the first hour, but later, S. typhimurium always exceeded S. enteritidis by the growth dynamics. The competitive advantage of S. typhimurium was observed both in the absence and presence of 60-MDa virulence plasmid.

摘要

我们研究了肠炎沙门氏菌和鼠伤寒沙门氏菌在这些微生物于体外形成的微生物联合体中的相互作用。结果发现，在LB肉汤中的微生物联合体里，鼠伤寒沙门氏菌抑制了肠炎沙门氏菌的繁殖，这证明了其更强的竞争力。6小时后培养基中鼠伤寒沙门氏菌的浓度达到细菌总数的92 - 93%。仅在最初1小时观察到肠炎沙门氏菌和鼠伤寒沙门氏菌种群的平行生长，但之后，从生长动态来看鼠伤寒沙门氏菌总是超过肠炎沙门氏菌。无论有无60-MDa毒力质粒，都观察到了鼠伤寒沙门氏菌的竞争优势。